2-Methyl-2-acetyl-5-pentanolid | 53604-61-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 2-Methyl-2-acetyl-5-pentanolid
• 英文别名: 3-Ethyl-3-methyloxan-2-one
• CAS: 53604-61-8
• 化学式: C₈H₁₄O₂
• 分子量: 142.198
• InChiKey: HNDMSFQIRXXSBX-UHFFFAOYSA-N

物化性质

• 沸点：
  221.2±8.0 °C(Predicted)
• 密度：
  0.948±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲酸 、 4-Methyl-hexan-1,4-diol 在 硫酸 作用下， 反应 1.3h， 以92%的产率得到2-Methyl-2-acetyl-5-pentanolid
  参考文献：
  名称：

  在浓硫酸存在下通过甲酸或铜 (I) 羰基化一级、三级 1,4-二醇的羧化反应，简便且高度选择性地合成 2,2-二烷基-1,5-内酯

  摘要：

  在室温和大气压下，在 97∼100% H2SO4 存在下，伯、叔 1,4-二醇与 100% 甲酸或铜 (I) 羰基化合物和一氧化碳的羧化反应得到 2,2-二烷基取代的 1 ,5-内酯产量高。

  DOI：

  10.1246/cl.1982.1187

文献信息

• TAKAHASHI, YUKIO;YONEDA, NORIHIKO;NAGAI, HIROSHI, CHEM. LETT., 1982, N 8, 1187-1188
  作者：TAKAHASHI, YUKIO、YONEDA, NORIHIKO、NAGAI, HIROSHI

  DOI：——

  日期：——
• (METH)ACRYLATE COMPOUND, (METH)ACRYLIC COPOLYMER AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20160347896A1

  公开（公告）日：2016-12-01

  The present invention provides a resist or a compound for use as a resist, which is highly sensitive and well-balanced without losing the fundamental physical properties required as a chemically amplified resist (e.g., resolution, line edge roughness (LER)). The present invention is directed to a (meth)acrylate compound represented by general formula (1) and a process for preparation thereof, as well as a (meth)acrylic copolymer obtainable by polymerization of the (meth)acrylate compound of general formula (1) and a photosensitive resin composition thereof: (wherein R 1 represents a hydrogen atom or a methyl group, R 2 represents a linear or branched alkyl group containing 2 to 4 carbon atoms, and each R 3 may be the same or different and represents a group represented by the following formula (2) or (3), etc.) (provided that formulae (2) and (3) are as defined in the specification of the present application).
• US9951163B2
  申请人：——

  公开号：US9951163B2

  公开（公告）日：2018-04-24
• FACILE AND HIGHLY SELECTIVE SYNTHESIS OF 2,2-DIALKYL-1,5-LACTONES BY THE CALBOXYLATION OF PRIMARY, TERTIARY-1,4-DIOLS WITH FORMIC ACID OR COPPER(I)CARBONYLS IN THE PRESENCE OF CONCENTRATED SULFURIC ACID
  作者：Yukio Takahashi、Norihiko Yoneda、Hiroshi Nagai

  DOI：10.1246/cl.1982.1187

  日期：1982.8.5

  The carboxylation of primary, tertiary-1,4-diols with 100% formic acid or copper(I)carbonyls and carbon monoxide in the presence of 97∼100% H2SO4 at room temperature and under atmospheric pressure gave 2,2-dialkyl substituted 1,5-lactones in high yields.

  在室温和大气压下，在 97∼100% H2SO4 存在下，伯、叔 1,4-二醇与 100% 甲酸或铜 (I) 羰基化合物和一氧化碳的羧化反应得到 2,2-二烷基取代的 1 ,5-内酯产量高。