bis(4,5-diazafluoren-9-one)dibromocopper(II) | 211620-58-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: bis(4,5-diazafluoren-9-one)dibromocopper(II)
• 英文别名: Cu(dafone)2Br2；Cu(4,5-diazafluorene-9-one)2Br2；3,13-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-8-one;dibromocopper
• CAS: 211620-58-5
• 化学式: C₂₂H₁₂Br₂CuN₄O₂
• 分子量: 587.717
• InChiKey: DRNNRZNKQLEQAX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  4,5-二氮芴-9-酮 、 copper(ll) bromide 以 水 、 丙酮 为溶剂， 以77.6%的产率得到bis(4,5-diazafluoren-9-one)dibromocopper(II)
  参考文献：
  名称：

  基于铜（II）与4,5-二氮杂芴-9-one和溴配体以及脱氧核糖核酸相互作用的电化学生物传感器

  摘要：

  制备了4,5-二氮杂芴-9-一（达丰）和溴配体（[Cu（dafone）2 ] Br 2）的铜配合物，并与pH 8.0的双链鲑鱼精子DNA（dsDNA）相互作用。 Robinson（B–R）缓冲溶液是在玻璃碳电极（GCE）上通过电化学实验研究的。结果表明，Cu（dafone）2 Br 2可以通过插入方式主要与鲑鱼精子DNA链结合。计算每个鲑鱼精子dsDNA链的[Cu（dafone）2 ] Br 2的结合数和结合反应的平衡常数分别为3和2.8×10 12  L 3  mol -3。铜（重金属）2 Br 2被进一步用作通过差动脉冲伏安法（DPV）检测人乙型肝炎病毒（HBV）DNA片段的新型电化学DNA指示剂。探索了在杂交的dsDNA双链体和探针DNA之间发生的电化学反应的差异，以评估开发的电化学DNA生物传感器的选择性。所构建的电化学DNA生物传感器对于互补靶DNA实现了3.18×10 -9  mol

  DOI：

  10.1016/j.electacta.2007.10.079

文献信息

• Crystal structure and theoretical calculation of copper complexes with 4,5-diazafluoren-9-one
  作者：R. L. Zhang、J. S. Zhao、X. L. Xi、P. Yang、Q. Z. Shi

  DOI：10.1134/s1070328409010059

  日期：2009.1

  Five copper complexes with 4,5-diazafluoren-9-one have been reported. Some of their structures are determined by single crystal X-ray diffraction. On the basis of experimentation, all the complexes were calculated by DFT-B3LYP/LANL2DZ in Gaussian-98w. By analyzing the experimental and calculated values, it can be concluded, on the one hand, that the experimental results are proved thoroughly by the theoretical calculated results; on the other hand, the theoretical calculated results can deduce the experimental results reasonably well.
• Bis chelate Cu(II) complexes of dafone—synthesis, structural, EPR and optical spectral studies
  作者：Sindhu Menon、M.V. Rajasekharan

  DOI：10.1016/s0277-5387(98)00046-1

  日期：1998.7

  Three examples of Cu(II) complexes with dafone, Cu(dafone)(2)Br-2 (1), [Cu(dafone)(2)(H2O)(2)](NO3)(2) (2) and [Cu(dafone)(2)(H2O)(2)](ClO4)(2) (3) have been synthesized and characterized structurally and spectroscopically. All complexes show unsymmetric chelation of dafone with one Cu-N bond being much longer than the other. Powder diffuse reflectance spectra have been recorded for 1, 2 and the known complex, Cu(dafone)(2)Cl-2 (4) and correlated with the molecular g-values for this relatively new type of Cu(II) chromophore. Compounds 1 and 2 were found to be sensitive to grinding leading to additional EPR signals for 1 and changes in the X-ray powder diffraction patterns. (C) 1998 Elsevier Science Ltd. All rights reserved.