1-ethynylcyclopentyl pivalate | 1016668-80-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-ethynylcyclopentyl pivalate
• 英文别名: (1-Ethynylcyclopentyl) 2,2-dimethylpropanoate
• CAS: 1016668-80-6
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.274
• InChiKey: WWEMTEBTZNBLBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.52
• 重原子数：
  14.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  1-ethynylcyclopentyl pivalate 在 重铬酸吡啶 、 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 0.5h， 生成 1-(3-cyclohexyl-3-oxoprop-1-yn-1-yl)cyclopentyl pivalate
  参考文献：
  名称：

  Au-Catalyzed Pentannulation Reaction of Propargylic Esters Occurring at C(sp³)–H Site

  摘要：

  A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp(3))-H site to efficiently produce functionalized mono-, bis-, and tricyclic cyclopentenones.

  DOI：

  10.1021/acs.orglett.5b01983
• 作为产物：
  描述：

  在 甲醇 、 potassium carbonate 作用下， 反应 1.0h， 以513 mg的产率得到1-ethynylcyclopentyl pivalate
  参考文献：
  名称：

  Au-Catalyzed Pentannulation Reaction of Propargylic Esters Occurring at C(sp³)–H Site

  摘要：

  A gold-catalyzed cascade cyclization reaction of easily accessible propargylic esters to cyclopentenones has been developed. This transformation features an unprecedented pentannulation reaction of propargylic esters which occurs at an unactivated C(sp(3))-H site to efficiently produce functionalized mono-, bis-, and tricyclic cyclopentenones.

  DOI：

  10.1021/acs.orglett.5b01983

文献信息

• Fluorenes and Styrenes by Au(I)-Catalyzed Annulation of Enynes and Alkynes
  作者：David J. Gorin、Iain D. G. Watson、F. Dean Toste

  DOI：10.1021/ja710990d

  日期：2008.3.1

  Intermolecular annulation of enynes and propargyl esters to selectively produce styrenes or fluorenes is reported. The divergent arene syntheses involve a Au-catalyzed, two-pot, multistep process proceeding cis-diastereoselective cyclopropanation, cycloisomerization, and, finally, annulation or elimination.
• POLYMER, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20210096465A1

  公开（公告）日：2021-04-01

  A polymer comprising recurring units having a multiple bond-containing acid labile group, recurring units having a phenolic hydroxyl group, and recurring units adapted to generate an acid upon exposure is used to formulate a resist composition, which exhibits a high sensitivity, low LWR and improved CDU when processed by lithography using EUV of wavelength 13.5 nm.