1-(2,2,3,3-tetrafluoropropyloxy)-2-methylpropane | 1115941-61-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(2,2,3,3-tetrafluoropropyloxy)-2-methylpropane
• 英文别名: 1-(2,2,3,3-Tetrafluoropropyloxy)-2-methylpropane；2-methyl-1-(2,2,3,3-tetrafluoropropoxy)propane
• CAS: 1115941-61-1
• 化学式: C₇H₁₂F₄O
• 分子量: 188.165
• InChiKey: QRMZVGDEYISIRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  异丁醇 、 2,2,3,3-Tetrafluoropropyl chlorosulfite 在 N,N-二甲基甲酰胺 作用下， 以60%的产率得到1-(2,2,3,3-tetrafluoropropyloxy)-2-methylpropane
  参考文献：
  名称：

  Features of catalysis in the reaction of polyfluoroalkyl chlorosulfites with saturated monohydric alcohols

  摘要：

  Synthetic opportunities and mechanism of catalysis of the reaction of polyfluororalkylchlorosulfites with saturated monohydric alcohols are considered. Kinetic measurements and quantum-chemical calculations showed that polyfluoroalkylation of these compounds proceeded through the step of complex formation involving reagents and catalyst followed by liberation of hydrogen chloride and sulfur dioxide and formation of polyfluoroalkyl ethers.

  DOI：

  10.1134/s1070363208110169

文献信息

• Features of catalysis in the reaction of polyfluoroalkyl chlorosulfites with saturated monohydric alcohols
  作者：A. I. Rakhimov、A. V. Nalesnaya、R. V. Fisechko

  DOI：10.1134/s1070363208110169

  日期：2008.11

  Synthetic opportunities and mechanism of catalysis of the reaction of polyfluororalkylchlorosulfites with saturated monohydric alcohols are considered. Kinetic measurements and quantum-chemical calculations showed that polyfluoroalkylation of these compounds proceeded through the step of complex formation involving reagents and catalyst followed by liberation of hydrogen chloride and sulfur dioxide and formation of polyfluoroalkyl ethers.