| 1394245-93-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• CAS: 1394245-93-2
• 化学式: C₁₈H₃₈O₆Si₂
• 分子量: 406.667
• InChiKey: PPGLNXQFFLACKW-LJISPDSOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

文献信息

• Solid-phase synthesis of benzazoles, quinazolines, and quinazolinones using an alkoxyamine linker
  作者：Kota Yamaguchi、Takeshi Noda、Yusuke Higuchi、Naoyuki Aoki、Rika Yamaguchi、Miwa Kubo、Kenichi Harada、Yoshiyasu Fukuyama、Hideaki Hioki

  DOI：10.1016/j.tetlet.2014.08.095

  日期：2014.10

  was applied for the solid-phase synthesis of benzazoles, quinazolines, and quinazolinones. Aromatic aldehydes were anchored by aldoxime linkage. After some reactions on a solid support, the products were cleaved with paraformaldehyde under the acidic conditions to afford the corresponding aldehydes, which were subsequently subjected to oxidative coupling with 2-substituted anilines under air atmosphere

  将烷氧基胺接头用于苯并唑，喹唑啉和喹唑啉酮的固相合成。芳香醛通过醛肟键锚定。在固体载体上进行一些反应后，将产物在酸性条件下用低聚甲醛裂解，得到相应的醛，随后将其与2-取代的苯胺在空气气氛下进行氧化偶联，得到所需的化合物。
• Solid-phase synthesis of benzothiazoles using an alkoxyamine linker
  作者：Hideaki Hioki、Kimihito Matsushita、Takeshi Noda、Kota Yamaguchi、Miwa Kubo、Kenichi Harada、Yoshiyasu Fukuyama

  DOI：10.1016/j.tetlet.2012.06.008

  日期：2012.8

  An alkoxyamine linker was applied for the solid-phase synthesis of benzothiazoles. The substrate was anchored by aldoxime linkage and products were cleaved from the solid-support by aldoxime–imine exchange coupled with air-oxidation under the weakly acidic conditions. The tether is highly robust under Mitsunobu reaction, nucleophilic substitution reaction, and Pd-catalyzed reaction conditions.

  将烷氧基胺接头用于苯并噻唑的固相合成。底物通过醛肟键固定，在弱酸性条件下，通过醛肟-亚胺交换结合空气氧化作用，将产物从固相支持物上裂解下来。该系链在Mitsunobu反应，亲核取代反应和Pd催化的反应条件下具有很高的鲁棒性。
• First total synthesis and absolute stereochemical assignment of vittarilide-A, an antioxidant extractive component isolated from Vittaria anguste-elongata Hayata
  作者：Masaki Takahashi、Yusuke Murata、Yuki Hakamata、Kohei Suzuki、Tetsuya Sengoku、Hidemi Yoda

  DOI：10.1016/j.tet.2012.06.105

  日期：2012.9

  The first stereocontrolled synthesis of vittarilide-A and its C5-epimer was completed from D-glucuronolactone. Comparison with the spectroscopic properties reported for authentic material has given a clear indication as to the absolute stereochemistry of the natural vittarilide-A. (C) 2012 Elsevier Ltd. All rights reserved.