1-((10-camphorsulfonyl)oxy)acetophenone | 87456-41-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-((10-camphorsulfonyl)oxy)acetophenone
• 英文别名: α-(camphorsulfonyloxy)acetophenone；phenacyl [(1S,4R)-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonate
• CAS: 87456-41-5
• 化学式: C₁₈H₂₂O₅S
• 分子量: 350.436
• InChiKey: AYXDDWBZCHWXDJ-RDTXWAMCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.61
• 重原子数：
  24.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  77.51
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  D(+)-10-樟脑磺酸 在 水 作用下， 以 乙腈 为溶剂， 反应 0.75h， 生成 1-((10-camphorsulfonyl)oxy)acetophenone
  参考文献：
  名称：

  Preparation of [hydroxy(((+)-10-camphorsulfonyl)oxy)iodo]benzene and its reactivity toward carbonyl compounds

  摘要：

  DOI：

  10.1021/jo00288a053

文献信息

• Sol–gel immobilized aryl iodides for the catalytic oxidative α-tosyloxylation of ketones
  作者：Wusheng Guo、Amàlia Monge-Marcet、Xavier Cattoën、Alexandr Shafir、Roser Pleixats

  DOI：10.1016/j.reactfunctpolym.2012.10.011

  日期：2013.1

  Abstract New hybrid silica materials M1–M4, derived from mono and bis-silylated aryl iodides, have been prepared via sol–gel processes, either by the hydrolytic polycondensation of a bis-silylated monomer or by the co-gelification of a monosilylated precursor with tetraethylorthosilicate. They have been fully characterized by elemental analysis, 13C and 29Si CP-MAS solid state NMR, IR, TGA, and nitrogen-sorption

  摘要由单硅烷化和双硅烷化的芳基碘衍生而来的新型杂化二氧化硅材料M1-M4是通过溶胶-凝胶法制备的，既可以通过双硅烷化单体的水解缩聚反应，也可以通过单硅烷化前体与硅烷基化的共凝胶化而制得。原硅酸四乙酯。它们已经通过元素分析，13C和29Si CP-MAS固态NMR，IR，TGA和氮吸附测量得到了充分表征。这些有机硅已成功地用作载体催化剂，在间氯过苯甲酸（m-CPBA）作为氧化剂存在下，在脂肪族酮的α-甲苯磺酰氧基化中得到了相应的α-甲苯磺酰氧基酮，其分离产率中等至良好。还已经研究了通过简单过滤的负载型催化剂的可回收性。
• Novel α-tosyloxylation of ketones catalyzed by the in situ generated hypoiodous acid from alkyl iodide
  作者：Bijun Zhang、Liuquan Han、Jiantao Hu、Jie Yan

  DOI：10.1016/j.tetlet.2014.08.093

  日期：2014.10

  Using a catalytic amount of 1-iodopropane, a novel and efficient procedure has been developed for direct preparation of alpha-tosyloxyketones from ketones. In this protocol, 1-iodopropane is first oxidized into iodosylpropane, which decomposes to form the key catalyst hypoiodous acid. With this method, not only alpha-tosyloxyketones, but also other alpha-sulfonyloxyketones have been prepared in moderate to good yields, which extends the application of alkyl substituted hypervalent iodine reagents in organic synthesis. (C) 2014 Elsevier Ltd. All rights reserved.
• HATZIGRIGORIOU, EVANGELIA;VARVOGLIS, ANASTASIOS;BAKOLA-CHRISTIANOPOULOU, +, J. ORG. CHEM., 55,(1990) N, C. 315-318
  作者：HATZIGRIGORIOU, EVANGELIA、VARVOGLIS, ANASTASIOS、BAKOLA-CHRISTIANOPOULOU, +

  DOI：——

  日期：——