| 1252031-96-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1252031-96-1
• 化学式: C₄₈H₅₃O₁₂P
• 分子量: 852.915
• InChiKey: MBRICEXNOMCNGK-UCJFMPODSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.57
• 重原子数：
  61.0
• 可旋转键数：
  21.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  118.6
• 氢给体数：
  0.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  2,3-di-O-benzyl-D-arabinose 、 在 三氟甲磺酸三甲基硅酯 作用下， 以 二氯甲烷 为溶剂， 生成 、 、 Bn(-2)[Bn(-3)][Bn(-5)]D-Araf(b1-5)[Bn(-2)][Bn(-3)]D-Araf(a1-5)[Bn(-2)][Bn(-3)]D-Araf 、
  参考文献：
  名称：

  Synthesis of partially benzylated arabinofuranosides, NMR analysis, and application to oligosaccharide synthesis

  摘要：

  The preparation and NMR analysis of 2,3-di-O-benzyl arabinofuranosides have been described. In DMSO-d(6), the sugar adopts a conformation in which the hydroxyl groups are in an equatorial position; the equilibrium composition is determined by steric factors. In CDCl3, the sugar adopts a conformation in which the intramolecular hydrogen bonding plays an important role in determining the equilibrium composition. The use of 2,3-di-O-benzyl arabinose in the synthesis of oligoarabinofuranosides enabled the synthesis of alpha- or beta-linked furanosides. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.06.033
• 作为产物：
  描述：

  2-chloro-2-oxo-1,3,2-dioxaphosphorinane 、 2',3',5'-tri-O-benzyl-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzyl-β-D-arabinofuranose 在 N-甲基咪唑 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of partially benzylated arabinofuranosides, NMR analysis, and application to oligosaccharide synthesis

  摘要：

  The preparation and NMR analysis of 2,3-di-O-benzyl arabinofuranosides have been described. In DMSO-d(6), the sugar adopts a conformation in which the hydroxyl groups are in an equatorial position; the equilibrium composition is determined by steric factors. In CDCl3, the sugar adopts a conformation in which the intramolecular hydrogen bonding plays an important role in determining the equilibrium composition. The use of 2,3-di-O-benzyl arabinose in the synthesis of oligoarabinofuranosides enabled the synthesis of alpha- or beta-linked furanosides. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.06.033