(E)-3-phenyl-2-(prop-1-en-1-yl)-6,7-dihydrobenzofuran-4(5H)-one | 1369592-54-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-3-phenyl-2-(prop-1-en-1-yl)-6,7-dihydrobenzofuran-4(5H)-one
• CAS: 1369592-54-0
• 化学式: C₁₇H₁₆O₂
• 分子量: 252.313
• InChiKey: JVERDFYCAVQDSY-FARCUNLSSA-N

反应信息

• 作为产物：
  描述：

  在 copper(II) choride dihydrate 、 氧气 、 sodium carbonate 、 palladium dichloride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 (Z)-3-phenyl-2-(prop-1-en-1-yl)-6,7-dihydrobenzofuran-4(5H)-one 、 (E)-3-phenyl-2-(prop-1-en-1-yl)-6,7-dihydrobenzofuran-4(5H)-one
  参考文献：
  名称：

  Palladium-catalyzed one-pot synthesis of polysubstituted furans from alkynoates and 2-yn-1-ols

  摘要：

  Easily accessible propargyl vinyl ethers are found to be acyclic precursors to construct furan derivatives. According to the reactive behavior of the substrates and the regulation of reaction conditions, three synthetic routes to polysubstituted furans via palladium-catalyzed reactions of propargyl vinyl ethers in situ-prepared from alkynoates and 2-yn-1-ols are presented herein. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and accessible starting materials. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.12.033