10-(2-hydroxy-phenyl)-10-oxo-decanoic acid | 101253-68-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10-(2-hydroxy-phenyl)-10-oxo-decanoic acid
• 英文别名: 10-(2-Hydroxy-phenyl)-10-oxo-decansaeure；10-(2-hydroxyphenyl)-10-oxodecanoic acid
• CAS: 101253-68-3
• 化学式: C₁₆H₂₂O₄
• 分子量: 278.348
• InChiKey: HRRLIWCFNWQDPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  10-氯-10-氧代癸酸甲酯 在 三氯化铝 作用下， 生成 10-(2-hydroxy-phenyl)-10-oxo-decanoic acid
  参考文献：
  名称：

  Tomino; Ashino, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1959, vol. 79, p. 96,99

  摘要：

  DOI：

文献信息

• Compounds and Compositions for Delivering Active Agents
  申请人：Gomez-Orellana Maria Isabel

  公开号：US20080255250A1

  公开（公告）日：2008-10-16

  Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

  提供用于传递活性成分的化合物和组合物。同时提供了管理和制备的方法。
• ARYL KETONE COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS
  申请人：Rath Parshuram

  公开号：US20080167217A1

  公开（公告）日：2008-07-10

  The present invention provides aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula or a salt thereof, where n=1 to 9, and R 1 to R 5 are independently hydrogen, C 1 to C 4 alkyl, C 1 to C 4 alkoxy, C 2 to C 4 alkenyl, halogen, hydroxyl, —NH—C(O)—CH 3 , or —O—C 6 H 5 .

  本发明提供了含有芳基酮化合物和组成物的方法，可以促进活性剂的传递。芳基酮化合物的化学式为或其盐，其中n = 1至9，R1至R5独立地为氢，C1至C4烷基，C1至C4烷氧基，C2至C4烯基，卤素，羟基，—NH—C（O）—CH3或—O—C6H5。
• Compounds and compositions for delivering active agents
  申请人：Emisphere Technologies, Inc.

  公开号：US08273794B2

  公开（公告）日：2012-09-25

  Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

  提供用于传递活性剂的化合物和组合物。同时提供了给药和制备方法。
• Aryl ketone compounds and compositions for delivering active agents
  申请人：Rath Parshuram

  公开号：US09035085B2

  公开（公告）日：2015-05-19

  The present invention provides aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula or a salt thereof, where n=1 to 9, and R1 to R5 are independently hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, C2 to C4 alkenyl, halogen, hydroxyl, —NH—C(O)—CH3, or —O—C6H5.

  本发明提供了含有芳基酮化合物的组合物，可促进活性剂的传递。 芳基酮化合物具有以下公式或其盐，其中n = 1至9，R1至R5独立地为氢，C1至C4烷基，C1至C4烷氧基，C2至C4烯基，卤素，羟基，—NH—C（O）—CH3或—O—C6H5。
• Treibs; Falk, Chemische Berichte, 1954, vol. 87, p. 345,348
  作者：Treibs、Falk

  DOI：——

  日期：——