N'-(4,5-difluoroacridin-9-yl)-4-methylbenzenesulfonohydrazide | 209460-07-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N'-(4,5-difluoroacridin-9-yl)-4-methylbenzenesulfonohydrazide
• CAS: 209460-07-1
• 化学式: C₂₀H₁₅F₂N₃O₂S
• 分子量: 399.421
• InChiKey: FPAVRGJJFDBXER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  79.5
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  N'-(4,5-difluoroacridin-9-yl)-4-methylbenzenesulfonohydrazide 在 sodium hydroxide 作用下， 以 四氢呋喃 、 水 、 乙二醇 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  4,5-bis(diphenylphosphino)acridine: A new type of tridentate phosphorus-nitrogen-phosphorus ligands

  摘要：

  Reaction of 4,5-difluoroacridine (8) with two equivalents of potassium diphenylphosphide (Ph2PK) yielded the title compound 3. Contrarily, diphenylphosphine (Ph2PH) reacted with 8 under addition, and 4,5-difluoro-9-diphenyl-9,10-dihydroacridine (12) was obtained. Compound 8 was prepared from 2-amino-3-fluorobenzoic acid (13) in a four step synthesis. As it is shown by the preparation of the metal complexes 4,5-bis(diphenylphosphino)acridine-palladium dichloride (16) and 4,5-bis(diphenylphosphino)acridine-molybdenum tricarbonyl (17), compound 3 is capable of acting as a tridentate PNP ligand which coordinates transition metals in an approximately "T-shaped" planar coordination geometry. Single crystal X-ray structure analyses are reported for 3 and 17. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10790-0
• 作为产物：
  描述：

  2-氟碘苯 在 铜 、 potassium carbonate 、 三氯氧磷 作用下， 以 四氢呋喃 、 氯仿 为溶剂， 反应 16.0h， 生成 N'-(4,5-difluoroacridin-9-yl)-4-methylbenzenesulfonohydrazide
  参考文献：
  名称：

  4,5-bis(diphenylphosphino)acridine: A new type of tridentate phosphorus-nitrogen-phosphorus ligands

  摘要：

  Reaction of 4,5-difluoroacridine (8) with two equivalents of potassium diphenylphosphide (Ph2PK) yielded the title compound 3. Contrarily, diphenylphosphine (Ph2PH) reacted with 8 under addition, and 4,5-difluoro-9-diphenyl-9,10-dihydroacridine (12) was obtained. Compound 8 was prepared from 2-amino-3-fluorobenzoic acid (13) in a four step synthesis. As it is shown by the preparation of the metal complexes 4,5-bis(diphenylphosphino)acridine-palladium dichloride (16) and 4,5-bis(diphenylphosphino)acridine-molybdenum tricarbonyl (17), compound 3 is capable of acting as a tridentate PNP ligand which coordinates transition metals in an approximately "T-shaped" planar coordination geometry. Single crystal X-ray structure analyses are reported for 3 and 17. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(97)10790-0