1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene | 1089179-12-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene
• 英文别名: 6-Ethyl-8-[2,4,5-tris(6-ethylquinolin-8-yl)phenyl]quinoline；6-ethyl-8-[2,4,5-tris(6-ethylquinolin-8-yl)phenyl]quinoline
• CAS: 1089179-12-3
• 化学式: C₅₀H₄₂N₄
• 分子量: 698.91
• InChiKey: GKKJIQWKXBYFTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.7
• 重原子数：
  54
• 可旋转键数：
  8
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  bis[dimethyl(μ-dimethylsulfide)platinum(II)] 、 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene 以 四氢呋喃 、 乙醚 为溶剂， 以85%的产率得到[Me4Pt2(1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene)]
  参考文献：
  名称：

  Diplatinum Complexes Supported by Novel Tetradentate Ligands with Quinoline Functionalities for Tandem C−Cl Activation and Dearomatization

  摘要：

  Three novel tetradentate ligands with quinoline functionalities, 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene, 1,2,4,5-tetrakis(6-tert-butylquinolin-8-yl)benzene, and 1,2,4,5-tetrakis(6-(trifluoromethoxy)quinolin-8-yl)benzene, were synthesized through a three-step protocol and fully characterized by NMR spectroscopic, elemental, and X-ray diffraction analyses. The dinuclear dimethylplatinum(II) complexes of these ligands readily activate C-Cl bonds of CHCl3 at ambient temperature, leading to the formation of the corresponding dinuclear Pt(IV) complex. In these reactions, the central phenyl rings of the tetradentate ligands are reduced to cyclohexadiene dianions and still retain their planarity.

  DOI：

  10.1021/om800893r

文献信息

• Reductive dearomatization of a substituted benzene triggered by a strong oxidant
  作者：Runyu Tan、Datong Song

  DOI：10.1039/b919233f

  日期：——

  platinum complexes Pt2Ph4LEt (1a) and Pt2Ph4LF (1b) (where LEt is 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene and LF is 1,2,4,5-tetrakis(6-trifluoromethoxylquinolin-8-yl)benzene) were synthesized and characterized. Triggered by an oxidant NCS, 1a and 1b displayed interesting reactivity of reductive dearomatization of the central phenyl rings of LEt and LF ligands respectively. The preliminary radical

  两个新的双核 铂 复合体 Pt 2 Ph 4 L Et（1a）及铂2 Ph 4 L F（1b）（其中大号的Et 是 1,2,4,5-四（6-乙基喹啉-8-基）苯 和 大号˚F 是 1,2,4,5-四（6-三氟甲氧基喹啉-8-基）苯）进行了合成和表征。由氧化剂NCS触发，1a和1b表现出有趣的中心还原性脱芳香化反应性苯基 的戒指 大号的Et 和 大号˚F配体。初步自由基清除剂 测试给出了一些机械方面的见解。
• Diplatinum Complexes Supported by Novel Tetradentate Ligands with Quinoline Functionalities for Tandem C−Cl Activation and Dearomatization
  作者：Runyu Tan、Peng Jia、Yingli Rao、Wenli Jia、Alen Hadzovic、Qing Yu、Xia Li、Datong Song

  DOI：10.1021/om800893r

  日期：2008.12.22

  Three novel tetradentate ligands with quinoline functionalities, 1,2,4,5-tetrakis(6-ethylquinolin-8-yl)benzene, 1,2,4,5-tetrakis(6-tert-butylquinolin-8-yl)benzene, and 1,2,4,5-tetrakis(6-(trifluoromethoxy)quinolin-8-yl)benzene, were synthesized through a three-step protocol and fully characterized by NMR spectroscopic, elemental, and X-ray diffraction analyses. The dinuclear dimethylplatinum(II) complexes of these ligands readily activate C-Cl bonds of CHCl3 at ambient temperature, leading to the formation of the corresponding dinuclear Pt(IV) complex. In these reactions, the central phenyl rings of the tetradentate ligands are reduced to cyclohexadiene dianions and still retain their planarity.