4-(4-methoxyphenyl)-5-((4-methoxyphenyl)diazenyl)thiazol-2-amine | 99481-90-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(4-methoxyphenyl)-5-((4-methoxyphenyl)diazenyl)thiazol-2-amine
• CAS: 99481-90-0
• 化学式: C₁₇H₁₆N₄O₂S
• 分子量: 340.406
• InChiKey: LVNIKKGFMGGCRM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.82
• 重原子数：
  24.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  82.09
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  乙烯基三乙氧基硅烷 、 4-(4-methoxyphenyl)-5-((4-methoxyphenyl)diazenyl)thiazol-2-amine 以 四氢呋喃 为溶剂， 反应 4.0h， 生成 4-(4-methoxyphenyl)-5-[(4-methoxyphenyl)diazenyl]-N-(2-triethoxysilylethyl)-1,3-thiazol-2-amine
  参考文献：
  名称：

  The synthesis of vinyltriethoxysilane-modified heteroaryl thiazole dyes and silica hybrid materials

  摘要：

  Hybrid materials composed of tetraethoxysilane and heteroaryl 4-substituent-2-aminothiazoles were prepared. 4-Substituted acetophenone, thiourea and iodide were used to generate the intermediate, 4-substituted-2-aminothiazole, as coupling component, which was then coupled with p-nitroaniline and p-methoxyaniline to yield heteroaryl 4-substitued thiazole azo dyes. The dyes subsequently underwent hydrolytic polycondensation with vinyltriethoxysilane and tetraethoxysilane to yield hybrid, heteroaryl thiazole azo dyes, whose chemical structure was characterized using FT-IR, Si-29 NMR, H-1 NMR and EDS. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2009.12.006
• 作为产物：
  描述：

  4-(4-甲氧基苯基)-1,3-噻唑-2-胺 、 甲氧苯胺 在 盐酸 、 硫酸 、 sodium nitrite 、 sodium carbonate 作用下， 以 水 为溶剂， 反应 0.33h， 生成 4-(4-methoxyphenyl)-5-((4-methoxyphenyl)diazenyl)thiazol-2-amine
  参考文献：
  名称：

  The synthesis of vinyltriethoxysilane-modified heteroaryl thiazole dyes and silica hybrid materials

  摘要：

  Hybrid materials composed of tetraethoxysilane and heteroaryl 4-substituent-2-aminothiazoles were prepared. 4-Substituted acetophenone, thiourea and iodide were used to generate the intermediate, 4-substituted-2-aminothiazole, as coupling component, which was then coupled with p-nitroaniline and p-methoxyaniline to yield heteroaryl 4-substitued thiazole azo dyes. The dyes subsequently underwent hydrolytic polycondensation with vinyltriethoxysilane and tetraethoxysilane to yield hybrid, heteroaryl thiazole azo dyes, whose chemical structure was characterized using FT-IR, Si-29 NMR, H-1 NMR and EDS. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2009.12.006