| 1315306-31-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• CAS: 1315306-31-0
• 化学式: C₁₁H₁₉O₆P
• 分子量: 278.242
• InChiKey: YQCPKPVRUIBAEM-UHFFFAOYSA-N

物化性质

• 沸点：
  357.8±25.0 °C(Predicted)
• 密度：
  1.20±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

反应信息

• 作为反应物：
  描述：

  在 ammonium acetate 、 sodium hydride 、 sulfur 、 溶剂黄146 作用下， 以 四氢呋喃 、 苯 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  Novel aminophosphonothiophene derivatives from β-keto-δ-carbethoxyphosphonates and phosphineoxides

  摘要：

  The reaction of -keto--carbethoxyphosphonates and phosphineoxides with active methylene nitriles leads to the corresponding phosphonoalkylidenes. Treatment of these compounds with sulfur, under the classical Gewald reaction conditions, gives a ca. 1:1 mixture of novel aminophosphonothiophene derivatives 3 and 3'. In order to improve the regioselectivity of the reaction, novel conditions have been developed for the Gewald condensation, in which we used an inorganic base NaH in THF as the solvent. These conditions afforded exclusively the 3-regioisomer in good yield. [image omitted].

  DOI：

  10.1080/17415993.2011.570763

文献信息

• Unusual Course of the Reaction of Lawesson’s Reagent with β-Phosphoryl- β’-carbethoxyhydrazones: First Synthesis of 5-Mercapto-3-(methylthiophosphoryl) pyrazoles
  作者：Emna Chebil、Soufiane Touil

  DOI：10.2174/157017812801264764

  日期：2012.5.1

  It is well known that Lawesson’s reagent (LR) reacts with hydrazone derivatives at 80 °C to yield 3-thioxo- 1,2,3-diazaphospholine derivatives. We show, in the present investigation, that the reaction of LR with β- phosphoryl-β’-carbethoxyhydrazones under the same conditions, took an entirely different course and gave a new type of pyrazole derivatives, the 5-mercapto-3-(methylthiophosphoryl)pyrazoles

  众所周知，Lawesson试剂（LR）在80℃下与衍生物反应以产生3-硫代-1,2,3-二氮杂磷酸衍生物。在本研究中，我们表明，在相同条件下，LR与β-磷酰基-β'-乙氧基hydr肼的反应采用了完全不同的过程，并得到了一种新型的吡唑衍生物，即5-巯基-3-（甲硫基磷酰基）吡唑类。