N-benzoylquinolinium iodide | 1283135-67-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-benzoylquinolinium iodide
• 英文别名: phenyl(quinolin-1-ium-1-yl)methanone;iodide
• CAS: 1283135-67-0
• 化学式: C₁₆H₁₂NO*I
• 分子量: 361.182
• InChiKey: PKHJAVOJZJRBNQ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.18
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  21
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  喹啉 、 苯甲醯碘 以81%的产率得到N-benzoylquinolinium iodide
  参考文献：
  名称：

  Acyl iodides in organic synthesis: XIII. Reaction of acyl iodides with nitrogen-containing heteroaromatic compounds

  摘要：

  Reactions of acetyl iodide with pyridine at room temperature and with quinoline both at 20-25A degrees C and on cooling to -50A degrees C involve dehydrohalogenation of acetyl iodide with formation of ketene and pyridinium or quinolinium iodides. The reaction of acetyl iodide with pyridine at -5 to -50A degrees C led to the formation of N-acetylpyridinium iodide. Benzoyl iodide reacted with both pyridine and quinoline at both -50A degrees C and at 20-25A degrees C to form stable N-benzoylpyridinium and N-benzoylquinolinium iodides. The reaction of pyrrole with acetyl iodide under analogous conditions was accompanied by polymerization.

  DOI：

  10.1134/s1070428010120122