| 1353553-28-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1353553-28-2
• 化学式: C₈H₁₅O₂P
• 分子量: 174.18
• InChiKey: NXUBRHARWZGNAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.65
• 重原子数：
  11.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  1-ethoxy-4-chloro-3-methyl-1,2-dihydrophosphinine oxide 在 甲酸铵 、 palladium dichloride 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以16%的产率得到
  参考文献：
  名称：

  A Study on the Reduction of 4-Chloro-1,2-Dihydrophosphinine Oxides by Transfer Hydrogenation

  摘要：

  Under the conditions of transfer hydrogenation by ammonium formate, the title compounds (6) were converted to a mixture of the corresponding 1,2,3,6-tetrahyidrophosphinine oxide (7), its dechlorinated derivative (8) and the respective 1,2,3,4,5,6-hexahydrophosphinine oxide (9). In the phenyl-substituted instance, the ratios of the components depended on the mode of heating (traditional heating or microwave irradiation), temperature, and the solvent (toluene or [bmim][BF4]) used. In the ethoxy-substituted series, the dechlorinated 1,2-dihydrophosphinine oxide (10b) was detected as an intermediate.

  DOI：

  10.1080/10426507.2011.608100