(2R,3R,4S,5S,6R)-2-(1'H-[2,2']Biindolyl-1-yl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol | 425376-30-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3R,4S,5S,6R)-2-(1'H-[2,2']Biindolyl-1-yl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
• CAS: 425376-30-3
• 化学式: C₂₂H₂₂N₂O₅
• 分子量: 394.427
• InChiKey: ODHZPVPBLPYMKN-QMCAAQAGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.76
• 重原子数：
  29.0
• 可旋转键数：
  3.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  110.87
• 氢给体数：
  5.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  丁炔二酸二甲酯 、 (2R,3R,4S,5S,6R)-2-(1'H-[2,2']Biindolyl-1-yl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 以 硝基苯 为溶剂， 以24%的产率得到11-((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-11,12-dihydro-11,12-diaza-indeno[2,1-a]fluorene-5,6-dicarboxylic acid dimethyl ester
  参考文献：
  名称：

  Short Step Syntheses of Indolo[2,3-a]carbazoles Carrying an Alkyl, Allyl, or a Glycosyl Group at the 11-Position and a Novel 6,7-Dihydro-13H-cyclopentano[mn]indolo[3,2-c]acridine Derivative

  摘要：

  Novel 1-alkyl-, 1-allyl-, and 1-beta-glycosyl-2,2'-biindolyls are prepared. Their Diels-Alder reaction produced 11-alkyl-, 11-allyl-, and 11-beta-glycosylindolo[2,3-a]carbazoles. Formation of a novel 6,7-dihydro-13H-cyclopentano[mn]indolo[3,2-c]acridine derivative is also reported.

  DOI：

  10.3987/com-01-s(k)40
• 作为产物：
  描述：

  2,3-dihydro-2,2'-biindolyl 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 生成 (2R,3R,4S,5S,6R)-2-(1'H-[2,2']Biindolyl-1-yl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Short Step Syntheses of Indolo[2,3-a]carbazoles Carrying an Alkyl, Allyl, or a Glycosyl Group at the 11-Position and a Novel 6,7-Dihydro-13H-cyclopentano[mn]indolo[3,2-c]acridine Derivative

  摘要：

  Novel 1-alkyl-, 1-allyl-, and 1-beta-glycosyl-2,2'-biindolyls are prepared. Their Diels-Alder reaction produced 11-alkyl-, 11-allyl-, and 11-beta-glycosylindolo[2,3-a]carbazoles. Formation of a novel 6,7-dihydro-13H-cyclopentano[mn]indolo[3,2-c]acridine derivative is also reported.

  DOI：

  10.3987/com-01-s(k)40