2-undecyl-1,4-benzoquinone | 52431-54-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-undecyl-1,4-benzoquinone
• 英文别名: 2-undecyl-p-benzoquinone；undecyl-[1,4]benzoquinone；Undecyl-[1,4]benzochinon；2-Undecyl-1,4-benzochinon；2-Undecylcyclohexa-2,5-diene-1,4-dione；2-undecylcyclohexa-2,5-diene-1,4-dione
• CAS: 52431-54-6
• 化学式: C₁₇H₂₆O₂
• 分子量: 262.392
• InChiKey: CJKAOSXSHTYWOT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-十一烷基苯酚 在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 反应 23.0h， 以5 mg的产率得到2-undecyl-1,4-benzoquinone
  参考文献：
  名称：

  Long chain alkyl phenols from the liverwort Schistochila appendiculata

  摘要：

  DOI：

  10.1016/s0031-9422(00)84775-5

文献信息

• Method of treatment of obesity
  申请人：Queen Mary University of London

  公开号：US10925849B2

  公开（公告）日：2021-02-23

  The present invention provides compositions and pharmaceutical compositions of GPR84 agonists and GPR120 agonists for us in the treatment of obesity and overweight. The invention provides methods of treatment accordingly as well as a kit for use in the treatment of obesity and overweight.

  本发明提供了用于治疗肥胖和超重的 GPR84 激动剂和 GPR120 激动剂的组合物和药物组合物。本发明提供了相应的治疗方法以及用于治疗肥胖和超重的试剂盒。
• Effects of reaction conditions on quinone/diquinone product ratios in the oxidation of 1,4-dimethoxybenzene derivatives with ceric ammonium nitrate
  作者：Brian E. Love、Brian C. Duffy、Alexander L. Simmons

  DOI：10.1016/j.tetlet.2014.02.017

  日期：2014.3

  Proper choice of reaction conditions allows formation of either the quinone or corresponding diquinone as the major product upon treatment of 2-alkyl-1,4-dimethoxybenzenes with ceric ammonium nitrate. (c) 2014 Elsevier Ltd. All rights reserved.
• Asano; Hase, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1940, vol. 60, p. 650,658
  作者：Asano、Hase

  DOI：——

  日期：——
• Jacobsen,N.; Torssell,K., Acta Chemica Scandinavica (1947), 1973, vol. 27, # 9, p. 3211 - 3216
  作者：Jacobsen,N.、Torssell,K.

  DOI：——

  日期：——
• Method Of Treatment Of Obesity
  申请人：Queen Mary University of London

  公开号：US20190105295A1

  公开（公告）日：2019-04-11

  The present invention provides compositions and pharmaceutical compositions of GPR84 agonists and GPR120 agonists for us in the treatment of obesity and overweight. The invention provides methods of treatment accordingly as well as a kit for use in the treatment of obesity and overweight.