8,11-dihydro-11-(4-hxdroxy-3-ethoxyphenyl)benzo[f]furo[3,4-b]quinolin-10(7H)-one | 878668-69-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 8,11-dihydro-11-(4-hxdroxy-3-ethoxyphenyl)benzo[f]furo[3,4-b]quinolin-10(7H)-one
• 英文别名: 8,11-dihydro-11-(4-hydroxy-3-ethoxyphenyl)benzo[f]furo[3,4-b]quinolin-10(7H)-one；8,11-Dihydro-11-(4-hydroxy-3-ethoxyphenyl)-benzo[f]furo[3,4-b]quinolin-10(7h)-one；17-(3-ethoxy-4-hydroxyphenyl)-14-oxa-11-azatetracyclo[8.7.0.02,7.012,16]heptadeca-1(10),2,4,6,8,12(16)-hexaen-15-one
• CAS: 878668-69-0
• 化学式: C₂₃H₁₉NO₄
• 分子量: 373.408
• InChiKey: LFFMQZLQYKIVRX-UHFFFAOYSA-N

物化性质

• 熔点：
  268-270 °C(Solvent: Ethanol; Benzene)
• 沸点：
  615.0±55.0 °C(predicted)
• 密度：
  1.39±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  67.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  (E,Z)-3-(4-hydroxy-3-ethoxybenzylidene)-tetrahydrofuran-2,4-dione 、 2-萘胺 以 乙醇 为溶剂， 以78%的产率得到8,11-dihydro-11-(4-hxdroxy-3-ethoxyphenyl)benzo[f]furo[3,4-b]quinolin-10(7H)-one
  参考文献：
  名称：

  Tetronic acid in reaction with aromatic aldehydes and 2-naphthylamine. Investigation of fluorescent and nonlinear-optical characteristics of compounds obtained

  摘要：

  By Knoevenagel condensation and by three-component condensation 3-arylmethylenetetrahydrofuran-2,4-diones and previously unknown 8,11-dihydro-11-arylbenzo[f]furo[3,4-b]quinolin-10(7H)-ones were respectively synthesized. The luminescent spectra and nonlinear-optical characteristics of compounds obtained were investigated.

  DOI：

  10.1134/s1070428008070142