2,6-dimethyl-4-(3,5-dimethyl-4-hydroxybenzylidene)-2,5-cyclohexadien-1-one | 107140-21-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,6-dimethyl-4-(3,5-dimethyl-4-hydroxybenzylidene)-2,5-cyclohexadien-1-one
• 英文别名: 4-(4-hydroxy-3,5-dimethyl-benzylidene)-2,6-dimethyl-cyclohexa-2,5-dienone；4-(4-Hydroxy-3,5-dimethyl-benzyliden)-2,6-dimethyl-cyclohexa-2,5-dienon；4-[(4-Hydroxy-3,5-dimethylphenyl)methylidene]-2,6-dimethylcyclohexa-2,5-dien-1-one
• CAS: 107140-21-6
• 化学式: C₁₇H₁₈O₂
• 分子量: 254.329
• InChiKey: HLXBAOPHHVWLQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,6-dimethyl-4-(3,5-dimethyl-4-hydroxybenzylidene)-2,5-cyclohexadien-1-one 、 溶剂黄146 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Fries; Brandes, Justus Liebigs Annalen der Chemie, 1939, vol. 542, p. 48,63

  摘要：

  DOI：
• 作为产物：
  描述：

  4,4'-亚甲基双(2,6-二甲苯酚) 在 silver(l) oxide 作用下， 以 乙醚 为溶剂， 反应 12.0h， 以86%的产率得到2,6-dimethyl-4-(3,5-dimethyl-4-hydroxybenzylidene)-2,5-cyclohexadien-1-one
  参考文献：
  名称：

  Surface-Accessible Detection Units in Self-Immolative Polymers Enable Translation of Selective Molecular Detection Events into Amplified Responses in Macroscopic, Solid-State Plastics

  摘要：

  This Communication describes a strategy for incorporating detection units onto each repeating unit of self-immolative CDr polymers. This strategy enables macroscopic plastics to respond quickly to specific applied molecular signals that react with the plastic at the solid-liquid interface between the plastic and surrounding fluid. The response is a signal-induced depolymerization reaction that is continuous and complete from the site of the reacted detection unit to the end of the polymer. Thus, this strategy retains the ability of CDr polymers to provide amplified responses via depolymerization while simultaneously enhancing the rate of response of CDr-based macroscopic plastics to specific applied signals. Depolymerizable poly(benzyl ethers) were used to demonstrate the strategy and now are capable of depolymerizing in the context of rigid, solid-state polymeric materials.

  DOI：

  10.1021/jacs.5b02799

文献信息

• ——
  作者：LYSENKO Z.、 BANCROFT E.

  DOI：——

  日期：——
• ——
  作者：LYSENKO Z.、 BANCROFT E. E.

  DOI：——

  日期：——
• Fries; Brandes, Justus Liebigs Annalen der Chemie, 1939, vol. 542, p. 48,63
  作者：Fries、Brandes

  DOI：——

  日期：——
• Surface-Accessible Detection Units in Self-Immolative Polymers Enable Translation of Selective Molecular Detection Events into Amplified Responses in Macroscopic, Solid-State Plastics
  作者：Kimy Yeung、Hyungwoo Kim、Hemakesh Mohapatra、Scott T. Phillips

  DOI：10.1021/jacs.5b02799

  日期：2015.4.29

  This Communication describes a strategy for incorporating detection units onto each repeating unit of self-immolative CDr polymers. This strategy enables macroscopic plastics to respond quickly to specific applied molecular signals that react with the plastic at the solid-liquid interface between the plastic and surrounding fluid. The response is a signal-induced depolymerization reaction that is continuous and complete from the site of the reacted detection unit to the end of the polymer. Thus, this strategy retains the ability of CDr polymers to provide amplified responses via depolymerization while simultaneously enhancing the rate of response of CDr-based macroscopic plastics to specific applied signals. Depolymerizable poly(benzyl ethers) were used to demonstrate the strategy and now are capable of depolymerizing in the context of rigid, solid-state polymeric materials.