α-D-GalpA-(1->2)-Glycerol | 73777-91-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-D-GalpA-(1->2)-Glycerol
• CAS: 73777-91-0
• 化学式: C₉H₁₆O₉
• 分子量: 268.221
• InChiKey: FIKFHOCRFKHFPJ-FIJBBSBCSA-N

物化性质

• 沸点：
  680.3±55.0 °C(Predicted)
• 密度：
  1.70±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.75
• 重原子数：
  18.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  156.91
• 氢给体数：
  6.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 α-D-GalpA-(1->2)-Glycerol 在 吡啶 作用下， 生成 三醋精
  参考文献：
  名称：

  Acylated oligosaccharides from Klebsiella K63 capsular polysaccharide: Depolymerization by partial hydrolysis and by bacteriophage-borne enzymes

  摘要：

  The extracellular polysaccharide from Klebsiella K63 is unique in having acetic and formic ester groups attached to the D-galactopyranosyluronic residues in the trisaccharide repeating-sequence. These O-acyl substituents are shown to be somewhat resistant to mild hydrolysis by both acid and alkali. Bacteriophage-induced depolymerization of the polysaccharide generated a series of acylated oligosaccharides comprising one, or more, repeating unit(s). By mild hydrolysis with acid, the same series of oligomers was released from the polysaccharide, together with the corresponding non-acylated compounds and the expected acylated and non-acylated aldobiouronic acids. A study of these oligosaccharides, as well as of a number of their related compounds, is described, with particular emphasis on the methods used to locate the formic and acetic ester groups. The location of the O-acyl substituents on the galactosyluronic residues was further supported by the results obtained from the high-resolution, 400-MHz, p.m.r. spectra and 13C-n.m.r. spectra of a number of the oligosaccharides.

  DOI：

  10.1016/s0008-6215(82)80011-6
• 作为产物：
  描述：

  在 sodium tetrahydroborate 、 sodium periodate 、 Amberlite IR-120 (H+) resin 、 三氟乙酸 作用下， 反应 20.0h， 生成 α-D-GalpA-(1->2)-Glycerol
  参考文献：
  名称：

  Acylated oligosaccharides from Klebsiella K63 capsular polysaccharide: Depolymerization by partial hydrolysis and by bacteriophage-borne enzymes

  摘要：

  The extracellular polysaccharide from Klebsiella K63 is unique in having acetic and formic ester groups attached to the D-galactopyranosyluronic residues in the trisaccharide repeating-sequence. These O-acyl substituents are shown to be somewhat resistant to mild hydrolysis by both acid and alkali. Bacteriophage-induced depolymerization of the polysaccharide generated a series of acylated oligosaccharides comprising one, or more, repeating unit(s). By mild hydrolysis with acid, the same series of oligomers was released from the polysaccharide, together with the corresponding non-acylated compounds and the expected acylated and non-acylated aldobiouronic acids. A study of these oligosaccharides, as well as of a number of their related compounds, is described, with particular emphasis on the methods used to locate the formic and acetic ester groups. The location of the O-acyl substituents on the galactosyluronic residues was further supported by the results obtained from the high-resolution, 400-MHz, p.m.r. spectra and 13C-n.m.r. spectra of a number of the oligosaccharides.

  DOI：

  10.1016/s0008-6215(82)80011-6