3-O-hypophosphite-1,2:5,6-O-diisopropylidene-α-D-glucofuranose | 869218-05-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-O-hypophosphite-1,2:5,6-O-diisopropylidene-α-D-glucofuranose
• CAS: 869218-05-3
• 化学式: C₁₂H₂₁O₇P
• 分子量: 308.268
• InChiKey: AVIPJVMYJGHETQ-HOTMZDKISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.07
• 重原子数：
  20.0
• 可旋转键数：
  3.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  72.45
• 氢给体数：
  0.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  3-O-hypophosphite-1,2:5,6-O-diisopropylidene-α-D-glucofuranose 、 三氯乙醛 以 氯仿 为溶剂， 反应 10.0h， 以40%的产率得到3-O-(1'-hydroxy-2',2',2'-trichloroethylphosphinite)-1,2:5,6-O-diisopropylidene-α-D-glucofuranose
  参考文献：
  名称：

  New Type of Hypophosphites

  摘要：

  Optimal conditions were found for the synthesis of hypophosphoric acid esters with the cyclic systems of cyclohexanal and 1,2;5,6-O-diisopropylidene-alpha-D-glycofuranose as an example. It was shown, that these hypophosphoric acid esters have high reactivity and are candidates for processes resulting in the formation of P-C bonds. The structure of the products was reliably supported by spectral methods.

  DOI：

  10.1080/104265090508262
• 作为产物：
  描述：

  双丙酮葡萄糖 在 吡啶 、 triethylammonium hypophosphite 、 三甲基乙酰氯 作用下， 以 氯仿 为溶剂， 反应 0.17h， 生成 3-O-hypophosphite-1,2:5,6-O-diisopropylidene-α-D-glucofuranose
  参考文献：
  名称：

  New Type of Hypophosphites

  摘要：

  Optimal conditions were found for the synthesis of hypophosphoric acid esters with the cyclic systems of cyclohexanal and 1,2;5,6-O-diisopropylidene-alpha-D-glycofuranose as an example. It was shown, that these hypophosphoric acid esters have high reactivity and are candidates for processes resulting in the formation of P-C bonds. The structure of the products was reliably supported by spectral methods.

  DOI：

  10.1080/104265090508262