(E)-1-triethysilylnon-1-en-4-ol | 1054612-35-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-1-triethysilylnon-1-en-4-ol
• 英文别名: (E)-1-triethylsilylnon-1-en-4-ol
• CAS: 1054612-35-9
• 化学式: C₁₅H₃₂OSi
• 分子量: 256.504
• InChiKey: RELJOXYOPMMRAD-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.92
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  三乙基硅烷 、 1-nonyn-4-ol 在 platinum(II) chloride 2-dicyclohexyl-phosphino-2',4',6'-triisopropylbiphenyl 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以96%的产率得到(E)-1-triethysilylnon-1-en-4-ol
  参考文献：
  名称：

  Xphos ligand and platinum catalysts: A versatile catalyst for the synthesis of functionalized β-(E)-vinylsilanes from terminal alkynes

  摘要：

  Hydrosilylation of functionalized terminal arylalkynes with a variety of silanes catalyzed by PtCl(2) or PtO(2) in the presence of the air-stable and bulky Xphos ligand was investigated. Regardless of the electronic nature ( electron withdrawing or donating group) and the position (o, m, p) of the substituents on the aromatic ring, a single beta-(E)-styrylsilanes was obtained in good to excellent yields. The regioselectivity of the H-Si bond addition was found to be governed by steric effects induced by the bulky Xphos ligand. A dramatic regioselectivity was also observed when functionalized terminal aliphatic alkynes were employed as a substrate and in these cases regioisomeric beta-(E)-vinylsilanes were generated with excellent selectivity. (c) 2008 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2008.05.028