Benzoic acid (2S,3R,4S,5S,6R)-6-azidomethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-[(2R,3R,4S,5R,6S)-4,5-diacetoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-p-tolylsulfanyl-tetrahydro-pyran-3-yloxy]-5-hydroxy-tetrahydro-pyran-3-yl ester | 634197-75-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Benzoic acid (2S,3R,4S,5S,6R)-6-azidomethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-[(2R,3R,4S,5R,6S)-4,5-diacetoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-p-tolylsulfanyl-tetrahydro-pyran-3-yloxy]-5-hydroxy-tetrahydro-pyran-3-yl ester
• CAS: 634197-75-4
• 化学式: C₄₂H₆₃N₃O₁₂SSi₂
• 分子量: 890.212
• InChiKey: WHJLNJXISGTOKR-OFROATJMSA-N

反应信息

• 作为反应物：
  描述：

  Benzoic acid (2S,3R,4S,5S,6R)-6-azidomethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-[(2R,3R,4S,5R,6S)-4,5-diacetoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-p-tolylsulfanyl-tetrahydro-pyran-3-yloxy]-5-hydroxy-tetrahydro-pyran-3-yl ester 在 氟化氢吡啶 作用下， 以 吡啶 为溶剂， 生成 Benzoic acid (2S,3R,4S,5R,6R)-6-azidomethyl-2-((2R,3R,4S,5R,6S)-4,5-diacetoxy-2-hydroxymethyl-6-p-tolylsulfanyl-tetrahydro-pyran-3-yloxy)-4,5-dihydroxy-tetrahydro-pyran-3-yl ester
  参考文献：
  名称：

  一种可编程的一锅寡糖合成方法，用于使天然产物的糖结构域多样化：以万古霉素为例。

  摘要：

  DOI：

  10.1002/anie.200351534
• 作为产物：
  描述：

  Acetic acid (2S,3R,4S,5R,6R)-4-acetoxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-5-hydroxy-2-p-tolylsulfanyl-tetrahydro-pyran-3-yl ester 、 Benzoic acid (2S,3R,4S,5S,6R)-6-azidomethyl-4-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-2-p-tolylsulfanyl-tetrahydro-pyran-3-yl ester 在 N-碘代丁二酰亚胺 、 三氟甲磺酸 作用下， 以45%的产率得到Benzoic acid (2S,3R,4S,5S,6R)-6-azidomethyl-4-(tert-butyl-dimethyl-silanyloxy)-2-[(2R,3R,4S,5R,6S)-4,5-diacetoxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-p-tolylsulfanyl-tetrahydro-pyran-3-yloxy]-5-hydroxy-tetrahydro-pyran-3-yl ester
  参考文献：
  名称：

  一种可编程的一锅寡糖合成方法，用于使天然产物的糖结构域多样化：以万古霉素为例。

  摘要：

  DOI：

  10.1002/anie.200351534