| 1447729-41-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1447729-41-0
• 化学式: C₄₀H₄₃N₃O₁₁
• 分子量: 741.795
• InChiKey: UUZMHDPQSOUEQG-UDGMINNCSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium hypochlorite 、 2,2,6,6-四甲基哌啶氧化物 、 (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate 、 camphor-10-sulfonic acid 、 四丁基氟化铵 、 lithium perchlorate 、 碳酸氢钠 、 cesium fluoride 、 sodium bromide 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 水 、 乙酸乙酯 、 甲苯 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of β-d-GalNAc(4,6-diS)(1–4)[α-l-Fuc(2,4-diS)(1–3)]-β-d-GlcA, a novel trisaccharide unit of chondroitin sulfate with a fucose branch

  摘要：

  Novel glycosaminoglycans isolated from the body wall of sea cucumbers consist of chondroitin sulfates like polysaccharides. We have synthesized a representative repeating trisaccharide composed of a chondroitin backbone having a fucose (Fuc) branch at O-3 of glucuronic acid (GlcA), beta-D-GalNac(4,6-diS)(1-4)[alpha-L-Fuc(2,4-diS)(1-3)]-beta-D-GlcA, in a stereocontrolled manner. Regiospecific sulfation at 04,6 and O-2,4 of the N-acetylgalactosamine (GalNAc) and Fuc residues, respectively, was successfully achieved. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.064
• 作为产物：
  描述：

  在 sodium methylate 作用下， 以 甲醇 为溶剂， 以86%的产率得到
  参考文献：
  名称：

  Synthesis of β-d-GalNAc(4,6-diS)(1–4)[α-l-Fuc(2,4-diS)(1–3)]-β-d-GlcA, a novel trisaccharide unit of chondroitin sulfate with a fucose branch

  摘要：

  Novel glycosaminoglycans isolated from the body wall of sea cucumbers consist of chondroitin sulfates like polysaccharides. We have synthesized a representative repeating trisaccharide composed of a chondroitin backbone having a fucose (Fuc) branch at O-3 of glucuronic acid (GlcA), beta-D-GalNac(4,6-diS)(1-4)[alpha-L-Fuc(2,4-diS)(1-3)]-beta-D-GlcA, in a stereocontrolled manner. Regiospecific sulfation at 04,6 and O-2,4 of the N-acetylgalactosamine (GalNAc) and Fuc residues, respectively, was successfully achieved. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.05.064