2-(β-chloroethoxy)cyclohexanol | 322642-29-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(β-chloroethoxy)cyclohexanol
• 英文别名: 2-(2-chloroethoxy)cyclohexan-1-ol
• CAS: 322642-29-5
• 化学式: C₈H₁₅ClO₂
• 分子量: 178.659
• InChiKey: SITHOFIVGSUPFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(β-chloroethoxy)cyclohexanol 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 以60%的产率得到trans-2,5-dioxabicyclo[4.4.0]decane
  参考文献：
  名称：

  Electrochemical transformations of monooxa- and dioxabicycloalkenes and-bicycloalkanes

  摘要：

  Electrolysis of 2-oxa- and 2,5-dioxabicyclo[n.4.0]alk-1(6)-enes (n = 4, 10) under conditions of direct undivided anodic oxidation in methanol results in their electrochemical mono- and dimethoxylation; electrolysis of the corresponding 2-oxa- and 2,5-dioxabicycloalkanes involves electrochemical cleavage of the bridging carbon-carbon bonds followed by electrooxidative transformation into methyl omega-(2-methoxytetrahydrofuryl)-, omega-(dimethoxymethyl)-, and omega-(1,3-dioxolan-2-yl)alkanoates.

  DOI：

  10.1007/bf02494854
• 作为产物：
  描述：

  氧化环己烯 、 2-氯乙醇 在 氢气 作用下， 生成 2-(β-chloroethoxy)cyclohexanol
  参考文献：
  名称：

  Electrochemical transformations of monooxa- and dioxabicycloalkenes and-bicycloalkanes

  摘要：

  Electrolysis of 2-oxa- and 2,5-dioxabicyclo[n.4.0]alk-1(6)-enes (n = 4, 10) under conditions of direct undivided anodic oxidation in methanol results in their electrochemical mono- and dimethoxylation; electrolysis of the corresponding 2-oxa- and 2,5-dioxabicycloalkanes involves electrochemical cleavage of the bridging carbon-carbon bonds followed by electrooxidative transformation into methyl omega-(2-methoxytetrahydrofuryl)-, omega-(dimethoxymethyl)-, and omega-(1,3-dioxolan-2-yl)alkanoates.

  DOI：

  10.1007/bf02494854