2,11-dioxa-1(2,15)-hexahelicenacycloundecaphane | 348165-10-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 2,11-dioxa-1(2,15)-hexahelicenacycloundecaphane
• 英文别名: Cgrlvrwgijdbnz-uhfffaoysa-；20,29-dioxaheptacyclo[17.10.7.04,31.07,32.010,33.013,34.016,35]hexatriaconta-1(30),2,4(31),5,7(32),8,10(33),11,13(34),14,16(35),17,19(36)-tridecaene
• CAS: 348165-10-6
• 化学式: C₃₄H₃₀O₂
• 分子量: 470.611
• InChiKey: CGRLVRWGIJDBNZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.4
• 重原子数：
  36
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,11-dioxa-1(2,15)-hexahelicenacycloundecaphane 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 3.5h， 生成 (+)-2,15-dihydroxyhexahelicene
  参考文献：
  名称：

  2,15-Dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor

  摘要：

  The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL can be efficiently as well as enantioselectively quenched by the enantiomers of several chiral amines and amino alcohols. Its high fluorescence intensity and its ability to enantiodiscriminate effectively makes it potentially useful for high-throughput screening of ee. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(01)00077-1
• 作为产物：
  描述：

  1,7-二(4-甲酰基苯氧基)庚烷 在 正丁基锂 、 碘 作用下， 以 四氢呋喃 、 正己烷 、 甲苯 为溶剂， 反应 6.0h， 生成 2,11-dioxa-1(2,15)-hexahelicenacycloundecaphane
  参考文献：
  名称：

  2,15-Dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor

  摘要：

  The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL can be efficiently as well as enantioselectively quenched by the enantiomers of several chiral amines and amino alcohols. Its high fluorescence intensity and its ability to enantiodiscriminate effectively makes it potentially useful for high-throughput screening of ee. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(01)00077-1

文献信息

• 2,15-Dihydroxy-hexahelicene (HELIXOL): synthesis and use as an enantioselective fluorescent sensor
  作者：Manfred T Reetz、Stefan Sostmann

  DOI：10.1016/s0040-4020(01)00077-1

  日期：2001.3

  The helical diol 2,15-dihydroxy-hexahelicene (HELIXOL) is an excellent fluorescence sensor for chiral amines and amino alcohols. The fluorescence of HELIXOL can be efficiently as well as enantioselectively quenched by the enantiomers of several chiral amines and amino alcohols. Its high fluorescence intensity and its ability to enantiodiscriminate effectively makes it potentially useful for high-throughput screening of ee. (C) 2001 Elsevier Science Ltd. All rights reserved.