4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl 3,4-anhydro-6-chloro-6-deoxy-β-D-fructofuranoside | 57783-44-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl 3,4-anhydro-6-chloro-6-deoxy-β-D-fructofuranoside
• 英文别名: 4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl-6-chloro-6-deoxy-β-D-fructofuranoside；4,6-dichloro-4,6-dideoxy-alpha-D-galacto-pyranosyl-6-chloro-6-deoxy-beta-D-fructofuranoside；4,6,6'-Trichlor-4,6,6'-trideoxy-galacto-sucrose；(2R,3R,4R,5R,6R)-5-chloro-6-(chloromethyl)-2-[(2S,3S,4S,5S)-5-(chloromethyl)-3,4-dihydroxy-2-(hydroxymethyl)oxolan-2-yl]oxyoxane-3,4-diol
• CAS: 57783-44-5
• 化学式: C₁₂H₁₉Cl₃O₈
• 分子量: 397.637
• InChiKey: WKUNDZOMGGNEMT-QBMZZYIRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  129
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  蔗糖 在 吡啶 、 磺酰氯 、 sodium iodide 作用下， 生成 4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl 3,4-anhydro-6-chloro-6-deoxy-β-D-fructofuranoside 、 4,6-dichloro-4,6-dideoxy-α-D-galactopyranosyl 3,4-anhydro-6-chloro-6-deoxy-β-D-ribo-hexulofuranoside 、 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4,6-dichloro-4,6-dideoxy-α-D-galactopyranoside
  参考文献：
  名称：

  强甜的氯脱氧蔗糖的合成：磺酰氯对蔗糖进行4'-氯化的机理

  摘要：

  摘要6-O-乙酰基蔗糖1与硫酰氯在氯仿-吡啶中反应，经脱氯硫化和乙酰化后，得到两种异构体2,3,6-三-O-乙酰基-4-氯-4-脱氧-α-的混合物d-吡喃半乳糖苷3- O-乙酰基1,4,6-三氯-1,4,6-丁氧基-β-d-六呋喃呋喃糖苷（6和7）和2,3,6-三-O-乙酰基-4-氯-4-脱氧-α-d-吡喃半乳糖苷3,4-二-O-乙酰基-1,6-二氯-1,6-二脱氧-β-d-果糖呋喃糖苷（4）。C-4，C-1'和C-6'的氯化反应是通过氯离子将最初形成的氯磺酰氧基直接置换而发生的，但4'-氯硫酸酯的置换在空间上受阻。4'-氯取代基的引入涉及中间体3'，4'-环氧化物通过氯离子的开环，核糖-环氧化物产生山梨醇-异构体6，而Lyxo-环氧化物产生果糖-异构体7。

  DOI：

  10.1016/0008-6215(87)80200-8

文献信息

• Taste potentiator compositions and edible confectionery and chewing gum products containing same
  申请人：Boghani Navroz

  公开号：US20060286203A1

  公开（公告）日：2006-12-21

  The present invention relates to compositions and edible orally delivered products, such as confectioneries and chewing gum, which include taste potentiators to enhance the perception of active substances contained therein. More specifically, some embodiments provide potentiator compositions, which include at least one active substance and at least one taste potentiator. The active substance and/or taste potentiator may be encapsulated in some embodiments to modify the release rate of the composition upon consumption.

  本发明涉及含有口味增强剂的组合物和可口服产品，例如糖果和口香糖，以增强其中所含活性物质的感知。更具体地，一些实施例提供了口味增强剂组合物，其中包括至少一种活性物质和至少一种口味增强剂。在某些实施例中，活性物质和/或口味增强剂可能被封装以修改在消费时的组合物释放速率。
• Taste potentiator compositions and beverages containing same
  申请人：Hargreaves A. Carole

  公开号：US20060286259A1

  公开（公告）日：2006-12-21

  The present invention relates to oral compositions and beverage products, which include taste potentiators to enhance the perception of active substances contained therein. More specifically, some embodiments provide potentiator compositions, which include at least one active substance, such as a sweetener, and at least one potentiator, such as a sweetness potentiator, which enhances the sweetness of the composition upon consumption.

  本发明涉及口腔制剂和饮料产品，其中包括味道增强剂，以增强其中所含活性物质的感知。更具体地，一些实施例提供增强剂组合物，其中包括至少一种活性物质，如甜味剂，和至少一种增强剂，如甜味增强剂，其在消费时增强了组合物的甜度。
• TASTE POTENTIATOR COMPOSITIONS AND EDIBLE CONFECTIONERY AND CHEWING GUM PRODUCTS CONTAINING SAME
  申请人：Boghani Navroz

  公开号：US20110274735A1

  公开（公告）日：2011-11-10

  The present invention relates to compositions and edible orally delivered products, such as confectioneries and chewing gum, which include taste potentiators to enhance the perception of active substances contained therein. More specifically, some embodiments provide potentiator compositions, which include at least one active substance and at least one taste potentiator. The active substance and/or taste potentiator may be encapsulated in some embodiments to modify the release rate of the composition upon consumption.

  本发明涉及到含有味道增强剂的组合物和口服可食用产品，例如糖果和口香糖，以增强其中所含活性物质的感知。更具体地说，一些实施例提供了增强剂组合物，其包括至少一种活性物质和至少一种味道增强剂。在某些实施例中，活性物质和/或味道增强剂可能被包封起来，以修改在食用时的组合物释放速率。
• CHOCOLATE COMPOSITIONS HAVING IMPROVED FLAVOUR CHARACTERISTICS
  申请人：Esteve Emilien Louis Joseph

  公开号：US20110052776A1

  公开（公告）日：2011-03-03

  The present invention relates to chocolate compositions which include taste potentiators to enhance the perception of flavouring elements contained therein. More specifically, some embodiments provide chocolate compositions comprising potentiator compositions, which include at least one flavouring element and at least one taste potentiator. The flavouring element and/or taste potentiator may be encapsulated in some embodiments to modify the release rate of the encapsulated element upon consumption.

  本发明涉及巧克力组合物，其包括味道增强剂以增强其中所含调味元素的感知。更具体地，一些实施例提供了包括增强剂组合物的巧克力组合物，其包括至少一种调味元素和至少一种味道增强剂。在某些实施例中，调味元素和/或味道增强剂可以被封装以修改在食用时所释放的封装元素的释放速率。
• OXALOACETIC ACID AND SALTS OF OXALOACETIC ACID AS A FLAVOR, AN ACIDIZING AND A PRESERVATIVE AGENTS AND METHODS FOR PREPARING AND USING SAME
  申请人：Cash Alan Brian

  公开号：US20110064679A1

  公开（公告）日：2011-03-17

  Provided herein is a method for flavoring an ingestible composition with an organoleptically effective amount of the flavoring agent. The flavoring agent may be used in a wide variety of ingestible vehicles such as chewing gum compositions, hard and soft confections, toothpaste, dairy products, beverage products including juice drinks and juice products, green vegetable and chicken products, salad dressings, deserts, bottled water, frozen treats and the like. The present invention also pertains to an ingestible composition comprising an ingestible vehicle and an organoleptically effective amount of the purified flavoring agent. The present invention also pertains to oxaloacetic acid and salts of oxaloacetic acid, represented by the formula, HOOCCH2CO—COOH and salts of the same. The invention further uses oxaloacetic acid and salts of oxaloacetic acid as a method to preservative in the preparation of ingestible compositions, without increase in toxicity. The invention further uses oxaloacetic acid as a ingestible acidizer, without increase in toxicity.

  本文提供了一种用食用调味剂调味的方法，其调味剂的感官效果足够。该调味剂可用于各种食用载体，例如口香糖组合物、硬和软糖果、牙膏、乳制品、饮料产品（包括果汁饮料和果汁产品）、绿色蔬菜和鸡肉制品、沙拉调味料、甜点、瓶装水、冷冻食品等。本发明还涉及一种包含食用载体和精制调味剂的感官效果量的食用组成物。本发明还涉及草酸乙酸及其盐，其化学式为HOOCCH2CO-COOH和其盐。该发明进一步使用草酸乙酸及其盐作为食用组成物制备中的防腐剂，而不增加毒性。该发明还进一步使用草酸乙酸作为食用酸化剂，而不增加毒性。