(E)-1-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)ethanone oxime | 1268260-76-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: (E)-1-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)ethanone oxime
• 英文别名: (NE)-N-[1-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]ethylidene]hydroxylamine
• CAS: 1268260-76-9
• 化学式: C₁₇H₁₄N₆O
• 分子量: 318.338
• InChiKey: PDJMTMOLLROCNQ-SSDVNMTOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  88.6
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• HETEROCYCLIC OXIME COMPOUNDS
  申请人：DAI Miao

  公开号：US20110065708A1

  公开（公告）日：2011-03-17

  The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).

  本发明涉及公式（I）的化合物及其盐： 其中取代基如规范中所定义；公式（I）的化合物用于人或动物体内的治疗，特别是针对c-Met酪氨酸激酶介导的疾病或情况；使用公式（I）的化合物制造治疗此类疾病的药物；包括公式（I）的化合物的制药组合物，可选地与联合伙伴一起使用，以及制备公式（I）的化合物的过程。
• Norbornene-Type Polymers, Compositions Thereof And Lithographic Processes Using Such Compositions
  申请人：Rhodes Larry F.

  公开号：US20110065878A1

  公开（公告）日：2011-03-17

  Embodiments of the present invention relate generally to non-self imagable and imagable norbornene-type polymers useful for immersion lithographic processes, methods of making such polymers, compositions employing such polymers and the immersion lithographic processes that make use of such compositions. More specifically the embodiments of the present invention are related to norbornene-type polymers useful for forming imaging layer and top-coat layers for overlying such imaging layers in immersion lithographic process and the process thereof.
• US8410264B2
  申请人：——

  公开号：US8410264B2

  公开（公告）日：2013-04-02
• US8507676B2
  申请人：——

  公开号：US8507676B2

  公开（公告）日：2013-08-13