1-(8-hydroxyquinoline-2-yl)propan-1-one | 1283725-91-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-(8-hydroxyquinoline-2-yl)propan-1-one
• 英文别名: 1-(8-Hydroxyquinolin-2-yl)propan-1-one
• CAS: 1283725-91-6
• 化学式: C₁₂H₁₁NO₂
• 分子量: 201.225
• InChiKey: WCLIBOJTLADIAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  50.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,6-二乙基苯胺 、 1-(8-hydroxyquinoline-2-yl)propan-1-one 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以24%的产率得到2-(1-(2,6-diethylphenylimino)propyl)quinolin-8-ol
  参考文献：
  名称：

  Methylaluminium 8-quinolinolates: synthesis, characterization and use in ring-opening polymerization (ROP) of ε-caprolactone

  摘要：

  2-(2,6-R苯基亚氨基)喹啉-8-醇(L1~L5, L1: R = Me, L2: R = Et, L3: R = iPr, L4: R = Cl, L5: R = F)与Me3Al的化学计量反应以良好收率得到了二聚体铝配合物[Me2AlL]2 (1~5)。相比之下，2-(1-(2,6-R-苯基亚氨基)丙基)喹啉-8-醇(L6~L10, L6: R = Me, L7: R = Et, L8: R = iPr, L9: R = Cl, L10: R = F)与Me3Al的化学计量反应得到了单核铝配合物Me2AlL (6~10)，同时伴随着副产物Me2AlL·Me3Al (11~15)的生成。所有甲基铝配合物均通过NMR光谱、元素分析进行了表征，配合物3、6和8的分子结构由单晶X射线衍射确定。铝化合物1~5对ε-己内酯的开环聚合无论有无BnOH的存在均无活性。相反，在BnOH存在下，单核铝化合物6~10能高效引发ε-己内酯的开环聚合;聚合过程表现出生长方式。

  DOI：

  10.1039/c0dt01207f

文献信息

• Synthesis, characterization, and ethylene (Co)polymerization behavior of trichlorotitanium 2-(1-(arylimino)propyl)quinolin-8-olates
  作者：Wei Huang、Wenjuan Zhang、Shaofeng Liu、Tongling Liang、Wen-Hua Sun

  DOI：10.1002/pola.24617

  日期：2011.4.15

  A series of trichlorotitanium complexes containing 2‐(1‐(arylimino)propyl)quinolin‐8‐olates was synthesized by stoichiometric reaction of titanium tetrachloride with the corresponding potassium 2‐(1‐(arylimino)propyl)quinolin‐8‐olates and was fully characterized by elemental analysis, nuclear magnetic resonance spectroscopy, and by single‐crystal X‐ray diffraction study of representative complexes

  通过四氯化钛与相应的2-（1-（（芳基）丙基）喹啉-8-钾钾的化学计量反应，合成了一系列含有2-（1-（（芳基）丙基）喹啉-8-酸酯的三氯钛配合物，通过元素分析，核磁共振波谱和代表性配合物的单晶X射线衍射研究得到充分表征。所有的钛配合物，当被甲基铝氧烷活化时，对乙烯聚合[高达1.15×10 6 g mol -1（Ti）h -1 ]和乙烯/α-烯烃共聚[高达1.54×10 6 g mol ]表现出高催化活性。-1（钛）h -1]。已证实共聚单体的掺入量分别高达2.82 mol％的1-己烯或1.94 mol％的1-辛烯。©2011 Wiley Periodicals，Inc. J Polym Sci A部分：Polym Chem，2011年
• Methylaluminium 8-quinolinolates: synthesis, characterization and use in ring-opening polymerization (ROP) of ε-caprolactone
  作者：Wen-Hua Sun、Miao Shen、Wenjuan Zhang、Wei Huang、Shaofeng Liu、Carl Redshaw

  DOI：10.1039/c0dt01207f

  日期：——

  The stoichiometric reactions of 2-(2,6-R-phenylimino)quinolin-8-ol (L1–L5, L1: R = Me, L2: R = Et, L3: R = iPr, L4: R = Cl, L5: R = F) with Me3Al afforded the dimeric aluminium complexes [Me2AlL]2 (1–5) in good yields. By contrast, stoichiometric reactions of 2-(1-(2,6-R-phenylimino)propyl) quinolin-8-ol (L6–L10, L6: R = Me, L7: R = Et, L8: R = iPr, L9: R = Cl, L10: R = F)) with Me3Al gave the mononuclear aluminium complexes Me2AlL (6–10) accompanied with by-products of the form Me2AlL·Me3Al (11–15). All methylaluminium complexes were characterized by NMR spectroscopy, elemental analysis, and the molecular structures of complexes 3, 6 and 8 were determined by single-crystal X-ray diffraction. Aluminium compounds 1–5 possessed negligible activity towards the ring-opening polymerization of ε-caprolactone either in the presence or absence of BnOH. In contrast, in the presence of BnOH, the mononuclear aluminium compounds 6–10 could efficiently initiate the ring-opening polymerization of ε-caprolactone; the polymerization proceeded in a living manner.

  2-(2,6-R苯基亚氨基)喹啉-8-醇(L1~L5, L1: R = Me, L2: R = Et, L3: R = iPr, L4: R = Cl, L5: R = F)与Me3Al的化学计量反应以良好收率得到了二聚体铝配合物[Me2AlL]2 (1~5)。相比之下，2-(1-(2,6-R-苯基亚氨基)丙基)喹啉-8-醇(L6~L10, L6: R = Me, L7: R = Et, L8: R = iPr, L9: R = Cl, L10: R = F)与Me3Al的化学计量反应得到了单核铝配合物Me2AlL (6~10)，同时伴随着副产物Me2AlL·Me3Al (11~15)的生成。所有甲基铝配合物均通过NMR光谱、元素分析进行了表征，配合物3、6和8的分子结构由单晶X射线衍射确定。铝化合物1~5对ε-己内酯的开环聚合无论有无BnOH的存在均无活性。相反，在BnOH存在下，单核铝化合物6~10能高效引发ε-己内酯的开环聚合;聚合过程表现出生长方式。