2,5-Bis(quinolin-8-yloxymethyl)-1,3,4-oxadiazole | 1048331-99-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2,5-Bis(quinolin-8-yloxymethyl)-1,3,4-oxadiazole
• CAS: 1048331-99-2
• 化学式: C₂₂H₁₆N₄O₃
• 分子量: 384.394
• InChiKey: ARJYCXHRWGDLPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  83.2
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  8-羟基喹啉 、 2,5-双氯甲基-1,3,4-噁二唑 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 以91%的产率得到2,5-Bis(quinolin-8-yloxymethyl)-1,3,4-oxadiazole
  参考文献：
  名称：

  Design of a Semirigid Molecule as a Selective Fluorescent Chemosensor for Recognition of Cd(II)

  摘要：

  A new 8-hydroxyquinoline-based chemosensor possessing a semirigid structure was designed, and its fluorescent sensing behavior toward metalions was investigated. A prominent fluorescence enhancement only for Cd2+ was found in aqueous methanol solution. The results clearly suggest that the specific semirigid structure could selectively accommodate Cd2+ according to ionic radius, which would effectively suppress the intramolecular radiationless transitions from the n pi* state to enhance the fluorescence response.

  DOI：

  10.1021/ol801382f