{[N-butyl-N-[3-(diisopropoxyphosphinoyl)propyl]-amino]methyl}dioctylphosphine oxide | 1167445-07-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物
• 英文名称: {[N-butyl-N-[3-(diisopropoxyphosphinoyl)propyl]-amino]methyl}dioctylphosphine oxide
• 英文别名: N-(dioctylphosphorylmethyl)-N-[3-di(propan-2-yloxy)phosphorylpropyl]butan-1-amine
• CAS: 1167445-07-9
• 化学式: C₃₀H₆₅NO₄P₂
• 分子量: 565.798
• InChiKey: VHORHXDQXLLVCR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  37
• 可旋转键数：
  27
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  diisopropyl 3-N-butylaminopropylphosphonate 、 dihexylphosphinous acid 、 三聚乙醛 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 以40%的产率得到{[N-butyl-N-[3-(diisopropoxyphosphinoyl)propyl]-amino]methyl}dioctylphosphine oxide
  参考文献：
  名称：

  Synthesis of novel mono-and bisaminophosphoryl compounds and their membrane transport properties for acidic substrates

  摘要：

  Some novel aminophosphoryl compounds were synthesized by the Kabachnik-Fields reaction. Their membrane transport properties for mono-and polyfunctional carboxylic acids with different number of functional groups were studied to establish that the transport rate of acidic substrates through liquid impregnated membranes increases in going from mono-to diphosphoryl carriers. Additional hydrophilic groups in the substrate molecule, too, affect transport efficiency.

  DOI：

  10.1134/s1070363208070062