(1s,4s)-4-(((2-fluorobenzylidene)amino)methyl)cyclohexane-1-carboxylic acid | 1032958-08-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1s,4s)-4-(((2-fluorobenzylidene)amino)methyl)cyclohexane-1-carboxylic acid
• CAS: 1032958-08-9
• 化学式: C₁₅H₁₈FNO₂
• 分子量: 263.312
• InChiKey: OJJXVEBLCZAWSZ-HAQNSBGRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.14
• 重原子数：
  19.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  49.66
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (1s,4s)-4-(((2-fluorobenzylidene)amino)methyl)cyclohexane-1-carboxylic acid 、 氯化钒 以 乙醇 、 水 为溶剂， 以68%的产率得到
  参考文献：
  名称：

  Synthesis, spectroscopy and antimicrobial activity of vanadium(III) and vanadium(IV) complexes involving Schiff bases derived from Tranexamic acid and X-ray structure of zwitter ion of Tranexamic acid

  摘要：

  This paper reports the synthesis of six new vanadium complexes of a Schiff base derived from Tranexamic acid. All the complexes were characterized by elemental analysis, infrared, electronic spectra, and mass spectrometry. FTIR data reveals that the Schiff base acts as a bidentate and the complexes exhibit the hexa-coordinated geometry in solid state. These complexes were screened for their biological activity against various bacterial and fungal strains. All the ligands show higher activity after complexation. The crystal structure of the Zwitter ion of the Tranexamic acid has been determined by X-ray single crystal diffraction.

  DOI：

  10.1134/s0036023607030163