6-(Hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2,4,5-triol | 93601-68-4

• 物质功能分类: 分析化学 - 标准品
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-(Hydroxymethyl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2,4,5-triol
• CAS: 93601-68-4；20429-79-2
• 化学式: C₁₂H₂₂O₁₁
• 分子量: 342.3
• InChiKey: HIWPGCMGAMJNRG-UHFFFAOYSA-N

物化性质

• 溶解度：
  DMSO：可溶；水溶性
• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

安全信息

• 储存条件：
  -20°C

制备方法与用途

Sophorose 是一种由酵母产生的微生物糖脂中的双糖成分，称为 sophorolipids。由于其疏水性，通常将它用作生物表面活性剂。此外，sophorolipid 还表现出抗菌、抗真菌、杀精子、杀病毒和抗癌等多种活性。在里氏木霉的发酵研究中，已鉴定出 Sophorose 是纤维素酶基因表达的有效诱导物。

文献信息

• Carohydrate-Ligand Conjugates and Their Application for the Analysis of Carbohydrate-Protein Interaction
  申请人：Suda Yasuo

  公开号：US20070287195A1

  公开（公告）日：2007-12-13

  A novel ligand conjugate which is effectively utilizable for analyzing a function of a protein; a ligand-supporting object; and a method of analyzing a protein. The ligand conjugate has a structure which comprises: a linker compound having a structure represented by the following General Formula (1): (wherein n and p each is an integer of 0 to 6) in which X is a structure comprising one, two, or three hydrocarbon derivative chains which have an aromatic amino group at the end and may have a carbon-nitrogen bond in the main chain, Y is a hydro-carbon structure containing one or more sulfur atoms, and Z is a straight-chain structure comprising a carbon-carbon bond or carbon-oxygen bond; and a sugar which has a reducing end and is bonded to the linker compound through the aromatic amino group.
• CARBOHYDRATE-LIGAND CONJUGATES AND THEIR APPLICATION FOR THE ANALYSIS OF CARBOHYDRATE-PROTEIN INTERACTION
  申请人：Japan Science and Technology Agency

  公开号：US20140295566A1

  公开（公告）日：2014-10-02

  A novel ligand conjugate which is effectively utilizable for analyzing a function of a protein; a ligand-supporting object; and a method of analyzing a protein. The ligand conjugate has a structure which comprises: a linker compound having a structure represented by the following General Formula (1): (wherein n and p each is an integer of 0 to 6) in which X is a structure comprising one, two, or three hydrocarbon derivative chains which have an aromatic amino group at the end and may have a carbon-nitrogen bond in the main chain, Y is a hydro-carbon structure containing one or more sulfur atoms, and Z is a straight-chain structure comprising a carbon-carbon bond or carbon-oxygen bond; and a sugar which has a reducing end and is bonded to the linker compound through the aromatic amino group.
• VACCINE AGAINST KLEBSIELLA PNEUMONIAE
  申请人：Idorsia Pharmaceuticals Ltd.

  公开号：US20210386845A1

  公开（公告）日：2021-12-16

  The present invention relates to a synthetic oligosaccharide of general formula (I): T*-[(—U x+4 —U x+3 —U x+2 —U x+1 —U x ) m —(V x+2 —V x+1 —V x ) 1-m -T-O-L-E that is related to Klebsiella pneumoniae serotype O3, O3b and/or O5 lipopolysaccharide and conjugate thereof. Said synthetic oligosaccharide, said conjugate and pharmaceutical composition containing said synthetic oligosaccharide or said conjugate are useful for prevention and/or treatment of diseases associated with Klebsiella pneumoniae . Furthermore, the synthetic oligosaccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Klebsiella pneumoniae serotype O3, O3b and/or O5 bacteria.
• US8765384B2
  申请人：——

  公开号：US8765384B2

  公开（公告）日：2014-07-01