3-Methoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde | 494-08-6

• 物质功能分类: 生物 - 细胞培养 - 添加剂
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Methoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde
• CAS: 494-08-6
• 化学式: C₁₄H₁₈O₈
• 分子量: 314.29
• InChiKey: LPRNQMUKVDHCFX-UHFFFAOYSA-N

物化性质

• 熔点：
  189-190°
• 比旋光度：
  D20 -89.9° (water)
• 沸点：
  574.7±50.0 °C(Predicted)
• 密度：
  1.481±0.06 g/cm3(Predicted)
• 溶解度：
  DMSO（轻微）、甲醇（轻微、加热）、水（轻微）
• LogP：
  -1.252 (est)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  126
• 氢给体数：
  4
• 氢受体数：
  8

安全信息

• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P305+P351+P338
• 危险性描述：
  H315,H319,H335
• 储存条件：
  2-8°C

制备方法与用途

生物活性方面，Glucovanillin可以从青荚中提取。它可以通过酶联合作用转化为香草醛，这一过程涉及细胞壁降解和葡萄糖苷水解。

文献信息

• Smoking composition containing a flavorant-release saccharide additive
  申请人：Philip Morris Products Inc.

  公开号：EP0506231A1

  公开（公告）日：1992-09-30

  This invention provides smoking compositions which contain a novel flavorant-release aditive of the formula: Under cigarette smoking conditions, a combustible filler and/or paper wrapper additive such as 4'-formyl-2'-methoxyphenyl 4,6-0-cinnamylidene-β-D-glucopyranoside pyrolyzes into cinnamaldehyde and vanillin flavorants as volatile components of the cigarette smoke.

  本发明提供的烟草组合物中含有一种新型的香料释放添加剂，其配方如下： 在卷烟吸食条件下，可燃填料和/或纸包装添加剂，如 4'-甲酰基-2'-甲氧基苯基 4,6-0-肉桂亚基-β-D-吡喃葡萄糖苷，会热解成肉桂醛和香兰素香料，作为卷烟烟雾中的挥发性成分。
• SUSTAINED-RELEASE AROMATIC AND METHOD OF DETECTING MICROORGANISM BY USING THE SAME
  申请人：KANEBO, LTD.

  公开号：EP0786247A1

  公开（公告）日：1997-07-30

  The present invention provides a sustained-release aromatic, characterized in that the aromatic comprises at least one perfume derivative as an active component selected from glycosides of perfumes, phosphoric acid ester derivatives of perfumes, amino acid derivatives of perfumes and carboxylic acid derivatives of perfumes, and contains no enzyme or acid which decomposes the perfume derivative, wherein the perfume derivative is decomposed by bacteria usually present on the skin or yeast to release a perfume component to exhibit aroma. The present invention also provides a method for the detection of micro-organisms using the aforesaid sustained-release aromatic. As the sustained-release aromatic of the present invention releases a perfume component only when it is decomposed by micro-organisms such as bacteria usually present on the skin or yeast, the amount of perfumes to be used can be extremely reduced. The sustained-release aromatic of the present invention is also excellent in keeping aroma. The stability with the passage of time of the sustained-release aromatic of the present invention is much better than that of the prior art because the perfume component is contained in the form of derivative. The sustained-release aromatic of the present invention is useful for applications on the skin, head skin or hair of human beings or animals, on clothes, or in drinks and foods, or as an indicator for detecting micro-organisms.

  本发明提供了一种缓释芳香剂，其特征在于该芳香剂包含至少一种香水衍生物作为活性成分，该香水衍生物选自香水的糖苷、香水的磷酸酯衍生物、香水的氨基酸衍生物和香水的羧酸衍生物，并且不含有分解香水衍生物的酶或酸，其中香水衍生物被通常存在于皮肤上的细菌或酵母分解，释放出香水成分，从而表现出芳香。本发明还提供了一种使用上述缓释芳香剂检测微生物的方法。由于本发明的缓释芳香剂只有在被通常存在于皮肤或酵母上的细菌等微生物分解时才会释放香水成分，因此可以大大减少香水的用量。本发明的缓释芳香剂在保持芳香方面也非常出色。由于香水成分以衍生物的形式存在，本发明的缓释芳香剂随着时间推移的稳定性比现有技术要好得多。本发明的缓释芳香剂可用于人或动物的皮肤、头皮或毛发、衣服、饮料和食品，或用作检测微生物的指示剂。
• Polymeric materials made from vanillin
  申请人：The United States of America, as represented by the Secretary of the Navy

  公开号：US10287237B1

  公开（公告）日：2019-05-14

  A method for converting vanillin to bis(cyanate) ester monomers, comprising treating vanillin with a reductive coupling agent to form at least one olefin. The olefin or olefins are treated with hydrogen and a metal catalyst to hydrogenate said olefin. The hydrogenated olefin or olefins are treated with at least one cyanogen halide and a base in an organic solvent to afford at least one olefin monomer. The olefin monomer or monomers are purified by recrystallization or precipitation from an organic solvent.

  一种将香兰素转化为双（氰酸酯）单体的方法，包括用还原偶联剂处理香兰素以形成至少一种烯烃。用氢气和金属催化剂处理烯烃，使烯烃氢化。氢化的烯烃或烯烃在有机溶剂中与至少一种卤化氰和一种碱处理，得到至少一种烯烃单体。通过重结晶或从有机溶剂中沉淀的方法纯化烯烃单体。
• Method for the production of natural botanical extracts
  申请人：Bartnick D. Daniel

  公开号：US20050074519A1

  公开（公告）日：2005-04-07

  Methods for producing natural botanical extracts, such as natural vanilla extracts, with low processing times and high efficiencies are provided. The methods include a high temperature extraction step and, optionally, an enzymatic treatment step. The natural vanilla extracts or other botanical extracts produced by the methods may provide the same degree of flavoring at lower concentrations than conventionally produced natural extracts.

  提供了生产天然植物提取物（如天然香草提取物）的方法，加工时间短，效率高。这些方法包括高温萃取步骤和可选的酶处理步骤。与传统生产的天然提取物相比，用这些方法生产的天然香草提取物或其他植物提取物可以较低的浓度提供相同程度的调味。
• EP1114173A4
  申请人：——

  公开号：EP1114173A4

  公开（公告）日：2005-02-16