2-allyloxy-quinoline | 945-84-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-allyloxy-quinoline
• 英文别名: 2-Allyloxyquinolin；2-Allyloxy-chinolin；2-[2-Propenyloxy]quinoline；2-prop-2-enoxyquinoline
• CAS: 945-84-6
• 化学式: C₁₂H₁₁NO
• 分子量: 185.225
• InChiKey: BCPYWLSHRUGNEM-UHFFFAOYSA-N

物化性质

• 沸点：
  107-108 °C(Press: 0.25 Torr)
• 密度：
  1.0912 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  22.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-氯喹啉 、 烯丙醇钠 在 烯丙醇 作用下， 生成 2-allyloxy-quinoline
  参考文献：
  名称：

  Reactions of Some Organometallic Compounds with 2-Substituted Quinolines^1a

  摘要：

  DOI：

  10.1021/ja01146a083

文献信息

• Novel Mesoionic Insecticidal Compound
  申请人：Nippon Kayaku Kabushiki Kaisha

  公开号：US20200017490A1

  公开（公告）日：2020-01-16

  The purpose of the present invention is to provide a mesoionic compound, which exhibits an improved controlling effect on various harmful organisms, or a salt thereof. A mesoionic compound represented by formula (1) (wherein: R 1 is selected from a hydrogen atom, etc.; R 2 represents an optionally substituted phenyl group; R 3 is selected from a hydrogen atom, etc.; R 4 is selected from a hydrogen atom, etc.; R 5 is selected from an optionally substituted ethylene group, etc.; and X is selected from an oxygen atom, etc.) or a salt thereof.

  本发明的目的是提供一种嵌环离子化合物，其在各种有害生物上表现出改进的控制效果，或其盐。由式（1）表示的嵌环离子化合物（其中：R1选自氢原子等；R2代表可选择取代的苯基团；R3选自氢原子等；R4选自氢原子等；R5选自可选择取代的乙烯基团等；X选自氧原子等）或其盐。
• Mesoionic Compound
  申请人：Nippon Kayaku Kabushiki Kaisha

  公开号：US20180310564A1

  公开（公告）日：2018-11-01

  The purpose of the present invention is to provide a mesoionic compound or a salt thereof that exhibits excellent control activity against various pests. Provided is a mesoionic compound represented by formula (1). (In the formula, Ra represents a hydrogen atom or a methyl group, R 1 represents a phenyl group or pyridyl group which is optionally substituted with up to two substituents selected independently from R 2 , and R 2 represents a hydrogen atom, a fluorine atom, a chlorine atom, a bromine atom, a methyl group, an ethyl group, an n-propyl group, an i-propyl group, a c-propyl group, an n-butyl group, an i-butyl group, an s-butyl group, a t-butyl group, a fluoromethyl group, a difluoromethyl group, a trifluoromethyl group, a methyloxy group, an ethyloxy group, an n-propyloxy group, an i-propyloxy group, a c-propyloxy group, an n-butyloxy group, an i-butyloxy group, a s-butyloxy group, a t-butyloxy group, an n-pentyloxy group, a trifluoromethyloxy group, a 2,2,2-trifluoroethyloxy group, a methylthio group, a methylsulfoxy group, a methylsulfonyl group, a vinyl group, an ethynyl group, etc.)

  本发明的目的是提供一种对各种害虫具有出色控制活性的噻唑离子化合物或其盐。提供了由式(1)表示的噻唑离子化合物。（在该式中，Ra代表氢原子或甲基基团，R1代表苯基或吡啶基，可选地取代高达两个从R2中独立选择的取代基，R2代表氢原子、氟原子、氯原子、溴原子、甲基基团、乙基基团、正丙基基团、异丙基基团、叔丙基基团、正丁基基团、异丁基基团、对丁基基团、叔丁基基团、氟甲基基团、二氟甲基基团、三氟甲基基团、甲氧基基团、乙氧基基团、正丙氧基基团、异丙氧基基团、叔丙氧基基团、正丁氧基基团、异丁氧基基团、对丁氧基基团、叔丁氧基基团、正戊氧基基团、三氟甲氧基基团、2,2,2-三氟乙氧基基团、甲硫基基团、甲磺氧基基团、甲磺酰基基团、乙烯基团、乙炔基团等。）
• Bicyclic androgen and progesterone receptor modulator compounds and methods
  申请人：Zhi Lin

  公开号：US20050288350A1

  公开（公告）日：2005-12-29

  The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.

  本发明涉及化合物、制药组合物和调节由AR和PR介导的过程的方法。更具体地，本发明涉及非甾体化合物和组合物，它们是高亲和力、高特异性的AR和PR激动剂、部分激动剂（即部分激活剂和/或组织特异性激活剂）和拮抗剂。还提供了制备这些化合物和制药组合物的方法，以及在它们的合成中使用的关键中间体。
• MESOIONIC COMPOUND
  申请人：Nippon Kayaku Kabushiki Kaisha

  公开号：EP3287457A1

  公开（公告）日：2018-02-28

  The purpose of the present invention is to provide a mesoionic compound or a salt thereof that exhibits excellent control activity against various pests. Provided is a mesoionic compound represented by formula (1). (In the formula, Ra represents a hydrogen atom or a methyl group, R1 represents a phenyl group or pyridyl group which is optionally substituted with up to two substituents selected independently from R2, and R2 represents a hydrogen atom, a fluorine atom, a chlorine atom, a bromine atom, a methyl group, an ethyl group, an n-propyl group, an i-propyl group, a c-propyl group, an n-butyl group, an i-butyl group, an s-butyl group, a t-butyl group, a fluoromethyl group, a difluoromethyl group, a trifluoromethyl group, a methyloxy group, an ethyloxy group, an n-propyloxy group, an i-propyloxy group, a c-propyloxy group, an n-butyloxy group, an i-butyloxy group, a s-butyloxy group, a t-butyloxy group, an n-pentyloxy group, a trifluoromethyloxy group, a 2,2,2-trifluoroethyloxy group, a methylthio group, a methylsulfoxy group, a methylsulfonyl group, a vinyl group, an ethynyl group, etc.)

  本发明的目的是提供一种中离子化合物或其盐，该化合物或其盐对各种害虫具有优异的防治活性。本发明提供了一种由式（1）表示的介离子化合物。 (式中，Ra 代表氢原子或甲基，R1 代表苯基或吡啶基，该苯基或吡啶基任选被最多两个独立于 R2 选出的取代基取代，R2 代表氢原子、氟原子、氯原子、溴原子、甲基、乙基、正丙基、异丙基、丙基、正丁基、异丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、正丁基、氟甲基、二氟甲基、三氟甲基、甲氧基、乙氧基、正丙氧基、一丙氧基、丙氧基、正 丁氧基、一丁氧基正戊氧基、三氟甲基氧基、2,2,2-三氟乙基氧基、甲硫基、甲硫基、甲磺酰基、乙烯基、乙炔基等。)
• NOVEL MESOIONIC INSECTICIDAL COMPOUND
  申请人：Nippon Kayaku Kabushiki Kaisha

  公开号：EP3521287A1

  公开（公告）日：2019-08-07

  The purpose of the present invention is to provide a mesoionic compound, which exhibits an improved controlling effect on various harmful organisms, or a salt thereof. A mesoionic compound represented by formula (1) (wherein: R1 is selected from a hydrogen atom, etc.; R2 represents an optionally substituted phenyl group; R3 is selected from a hydrogen atom, etc.; R4 is selected from a hydrogen atom, etc.; R5 is selected from an optionally substituted ethylene group, etc.; and X is selected from an oxygen atom, etc.) or a salt thereof.

  本发明的目的是提供一种对各种有害生物具有更好控制效果的介离子化合物或其盐。一种由式（1）代表的介离子化合物（其中：R1选自氢原子等；R2代表任选取代的苯基；R3选自氢原子等；R4选自氢原子等；R5选自任选取代的乙烯基等；X选自氧原子等）或其盐。