clusin | 86992-94-1

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 呋喃类木脂素
• 英文名称: clusin
• 英文别名: 4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-ol
• CAS: 86992-94-1
• 化学式: C₂₂H₂₆O₇
• 分子量: 402.444
• InChiKey: SOCNBZCAGNYAED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• [EN] LIGNAN COMPOSITIONS<br/>[FR] COMPOSITIONS DE LIGNANE
  申请人：ALPINIA LAUDANUM INST OF PHYTOPHARMACEUTICAL SCIENCES AG

  公开号：WO2014086480A1

  公开（公告）日：2014-06-12

  The present invention provides pharmaceutical compositions comprising lignans, which are useful in the treatment or prevention of tumour and/or cancer diseases, in particular for the treatment or prevention of hormone-dependent tumour and/or cancer diseases, such as prostate cancer. Furthermore, the present invention relates to a process for obtaining a lignan composition from lignan-containing plant material, such as from Piper cubeba L., as well as to the use of the lignan composition obtainable by such process as a medicament.