N-mercapto-4-formylcarbostyril | 402934-24-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-mercapto-4-formylcarbostyril
• 英文别名: 2-oxo-1-sulfanylquinoline-4-carbaldehyde
• CAS: 402934-24-1
• 化学式: C₁₀H₇NO₂S
• 分子量: 205.237
• InChiKey: ZEPFEQYCJVHPET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 N-mercapto-4-formylcarbostyril 在 吡啶 作用下， 生成 Thioacetic acid S-(4-formyl-2-oxo-2H-quinolin-1-yl) ester
  参考文献：
  名称：

  Isolation and identification of N-mercapto-4-formylcarbostyril, an antibiotic produced by Pseudomonas fluorescens

  摘要：

  Pseudomonas fluorescens strain G308 isolated from barley leaves produces a novel antibiotic substance that was purified by preparative TLC and HPLC and identified as N-mercapto-4-formylcarbostyril (Cbs) by LC/DAD, IR, LC-ES+/MS, LC-ES-/MS, GC-EI/MS, LC-HRES+ /MS, mass isotope ratios analysis, H-1 NMR and C-13 NMR analysis. The purified new antibiotic compound is effective against many phytopathogenic fungi in vitro. The compound inhibited Lit 25 ppm spore germination and germ tube growth of the following fungi, Fusarium oxysporum f. sp. lycopersici, Fusarium culmorum, Cladosporium cucumerinum and Colletotrichum lagenarium, At concentrations up to 125 ppm, the compound did not interfere with release of zoospores from sporangia and germination of encysted zoospores of Phytophthora infestans. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(01)00344-2