α-isomaltosyl α-glucoside | 103130-74-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-isomaltosyl α-glucoside
• 英文别名: isobemisiose；α-D-Glcp-(1→6)-α-D-Glcp-(1↔1)-α-D-Glcp；O-α-D-glucopyranosyl-(1->6)-α-D-glucopyranosyl-α-D-glucopyranoside；(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol
• CAS: 103130-74-1
• 化学式: C₁₈H₃₂O₁₆
• 分子量: 504.442
• InChiKey: JPQYDVAIBALJDC-WTRHKFRWSA-N

物化性质

• 沸点：
  867.0±65.0 °C(Predicted)
• 密度：
  1.80±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -6.3
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  269
• 氢给体数：
  11
• 氢受体数：
  16

反应信息

• 作为产物：
  描述：

  海藻糖 、 D-葡萄糖 以5%的产率得到
  参考文献：
  名称：

  AJISAKA, KATSUMI;FUJIMOTO, HIROSHI, CARBOHYDR. RES., 199,(1990) N, C. 227-234

  摘要：

  DOI：

文献信息

• Synthesis by an<i>α</i>-Glucosidase of Glycosyl-trehaloses with an Isomaltosyl Residue
  作者：Masashi Kurimoto、Tomoyuki Nishimoto、Tetsuya Nakada、Hiroto Chaen、Shigeharu Fukuda、Yoshio Tsujisaka

  DOI：10.1271/bbb.61.699

  日期：1997.1

  an isomaltosyl residue were synthesized by alpha-glucosidase from Aspergillus niger by using maltotetraose as a glucosyl donor and trehalose as the acceptor. The one trisaccharide and two tetrasaccharides formed were isolated by successive column chromatography. The results of an enzymatic digestion, methylation analysis, and 13C-NMR studies indicated that these oligosaccharides were alpha-isomaltosyl

  以麦芽四糖为葡萄糖基供体，以海藻糖为受体，通过黑曲霉的α-葡糖苷酶合成具有异麦芽糖基残基的糖基-海藻糖。通过连续柱色谱分离形成的一种三糖和两种四糖。酶消化，甲基化分析和13 C-NMR研究的结果表明，这些寡糖为α-异麦芽糖基α-葡萄糖苷，α-异麦芽三糖基α-葡萄糖苷和α-异麦芽糖苷。这些低聚糖没有被变形链球菌发酵成酸，它们有效地抑制了葡糖基转移酶从蔗糖中合成水不溶性葡聚糖。在人类肠道细菌的体外利用测试中，这些寡糖主要被双歧杆菌利用。
• Regioselective syntheses of trehalose-containing trisaccharides using various glycohydrolases
  作者：Katsumi Ajisaka、Hiroshi Fujimoto

  DOI：10.1016/0008-6215(90)84264-u

  日期：1990.6

  Two methods were investigated for the enzymic preparation of trehalose-containing trisaccharides. In the first, a solution of saccharides is circulated through an immobilized-glycosidase column and an activated-carbon column connected in series. In the second, two enzymes having different substrate specificities are sequentially used for condensation and subsequent specific hydrolysis. Thus, 3-O-beta-D-, 4-O-beta-D-, and 6-O-beta-D-galactopyranosyl-alpha,alpha-trehalose; 4-O-alpha-D- and 6-O-alpha-D-glucopyranosyl-alpha,alpha-trehalose; and 4-O-beta-D- and 6-O-beta-D-glucopyranosyl-alpha,alpha-trehalose were synthesized stereo- and regio-selectively.
• AJISAKA, KATSUMI;FUJIMOTO, HIROSHI, CARBOHYDR. RES., 199,(1990) N, C. 227-234
  作者：AJISAKA, KATSUMI、FUJIMOTO, HIROSHI

  DOI：——

  日期：——