glucose

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: glucose
• 英文别名: (3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
• 化学式: C₆H₁₂O₆
• 分子量: 180.158
• InChiKey: GZCGUPFRVQAUEE-YMFWUOAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  118
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  glucose 在 glucose oxidase 作用下， 以 aq. phosphate buffer 为溶剂， 反应 0.5h， 生成 gluconic acid
  参考文献：
  名称：

  Facile one-pot synthesis of Mn₃O₄ nanorods and their analytical application

  摘要：

  该研究首次实现了不使用模板和表面活性剂在室温水溶液中一锅合成 Mn3O4 纳米棒，为制备用于检测 H2O2 相关目标的各种金属纳米棒开辟了一条新途径。

  DOI：

  10.1039/d1nj02513a
• 作为产物：
  描述：

  果糖 在 2-氨基吡啶 、 溶剂黄146 作用下， 生成 glucose
  参考文献：
  名称：

  Development of a chemical strategy to produce rare aldohexoses from ketohexoses using 2-aminopyridine

  摘要：

  Rare sugars are monosaccharides that are found in relatively low abundance in nature. Herein, we describe a strategy for producing rare aldohexoses from ketohexoses using the classical Lobry de Bruyn-Alberda van Ekenstein transformation. Upon Schiff-base formation of keto sugars, a fluorescence-labeling reagent, 2-aminopyridine (2-AP), was used. While acting as a base catalyst, 2-AP efficiently promoted the ketose-to-aldose transformation, and acting as a Schiff-base reagent, it effectively froze the ketose-aldose equilibrium. We could also separate a mixture of Sor, Gul, and Ido in their Schiff-base forms using a normal-phase HPLC separation system. Although Gul and Ido represent the most unstable aldohexoses, our method provides a practical way to rapidly obtain these rare aldohexoses as needed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2011.09.021
• 作为试剂：
  描述：

  (R)-3-氧代-5-羟基-6-氰基己酸叔丁酯 在 glucose 、 aldo-keto reductase KmAKR 、 sodium hydroxide 作用下， 以 aq. phosphate buffer 为溶剂， 反应 3.7h， 以90.385%的产率得到
  参考文献：
  名称：

  Tailoring an aldo-keto reductase KmAKR for robust thermostability and catalytic efficiency by stepwise evolution and structure-guided consensus engineering

  摘要：

  DOI：

  10.1016/j.bioorg.2021.104712

文献信息

• HIGH-YIELD CONVERSION OF CELLULOSIC BIOMASS INTO FURANIC BIOFUELS AND VALUE-ADDED PRODUCTS
  申请人：Mascal Mark

  公开号：US20090234142A1

  公开（公告）日：2009-09-17

  Paper, cotton, corn stover, straw, and wood are converted into furanic products in high yields (based on their cellulose content) using a simple, inexpensive process involving concurrent hydrolysis, dehydration, and substitution reactions coupled with continuous extraction into an organic phase. In a simultaneous process, the hemicellulose fraction of these substrates is converted into furfural, and together these constitute an efficient means for the total exploitation of the carbohydrate content of biomass.

  纸张、棉花、玉米秸秆、稻草和木材通过一种简单、廉价的过程转化为高产量的呋喃类产品（基于它们的纤维素含量），该过程涉及同时水解、脱水和取代反应，并与连续萃取到有机相结合。在同时进行的过程中，这些底物的半纤维素部分被转化为糠醛，这两者共同构成了对生物质碳水化合物含量的有效利用手段。
• Development of a chemical strategy to produce rare aldohexoses from ketohexoses using 2-aminopyridine
  作者：Kayo Hasehira、Nobumitsu Miyanishi、Wataru Sumiyoshi、Jun Hirabayashi、Shin-ichi Nakakita

  DOI：10.1016/j.carres.2011.09.021

  日期：2011.12

  Rare sugars are monosaccharides that are found in relatively low abundance in nature. Herein, we describe a strategy for producing rare aldohexoses from ketohexoses using the classical Lobry de Bruyn-Alberda van Ekenstein transformation. Upon Schiff-base formation of keto sugars, a fluorescence-labeling reagent, 2-aminopyridine (2-AP), was used. While acting as a base catalyst, 2-AP efficiently promoted the ketose-to-aldose transformation, and acting as a Schiff-base reagent, it effectively froze the ketose-aldose equilibrium. We could also separate a mixture of Sor, Gul, and Ido in their Schiff-base forms using a normal-phase HPLC separation system. Although Gul and Ido represent the most unstable aldohexoses, our method provides a practical way to rapidly obtain these rare aldohexoses as needed. (C) 2011 Elsevier Ltd. All rights reserved.
• Facile one-pot synthesis of Mn₃O₄ nanorods and their analytical application
  作者：Lijun Xu、Lu Yang、Aihua Liu

  DOI：10.1039/d1nj02513a

  日期：——

  One-pot synthesis of Mn₃O₄ nanorods in aqueous solution at room temperature without using templates and surfactants was achieved for the first time, opening a new route for preparing various metal nanorods for detecting H₂O₂-related targets.

  该研究首次实现了不使用模板和表面活性剂在室温水溶液中一锅合成 Mn3O4 纳米棒，为制备用于检测 H2O2 相关目标的各种金属纳米棒开辟了一条新途径。