2,5-dimethyl-heptan-4-one | 40239-46-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,5-dimethyl-heptan-4-one
• 英文别名: sek.-Butyl-isobutyl-keton；2,5-Dimethyl-heptan-4-on；2,5-dimethylheptan-4-one
• CAS: 40239-46-1
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: AHXADOAHIKYQRT-UHFFFAOYSA-N

物化性质

• 沸点：
  165-167 °C
• 密度：
  0.812±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-甲基巴豆酰氯 在 palladium on activated charcoal 氢气 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 生成 2,5-dimethyl-heptan-4-one
  参考文献：
  名称：

  Dubois, Jacques-Emile; Lion, Claude; Arouisse, Abdelmajid, Bulletin des Societes Chimiques Belges, 1984, vol. 93, # 12, p. 1083 - 1088

  摘要：

  DOI：

文献信息

• PROCESS FOR REDUCING EMISSIONS OF VOLATILE ORGANIC COMPOUNDS FROM THE KETONIZATION OF CARBOXYLIC ACIDS
  申请人：Barnicki Scott Donald

  公开号：US20130310608A1

  公开（公告）日：2013-11-21

  Disclosed is a process for reducing the emission of volatile organic compounds that are produced during the ketonization of carboxylic acids to ketones. The ketonization of carboxylic acids produces a gaseous by-product stream containing carbon dioxide and volatile organic compounds. This gaseous by-product stream can be fed to a direct-fired furnace used to heat the ketonization reaction feed streams where the volatile organic compounds are destroyed by combustion in the furnace. The carbon dioxide stream further acts as a diluent for the fuel to the furnace.

  揭示了一种减少在羧酸酯化制备酮过程中产生的挥发性有机化合物排放的方法。羧酸酯化产生的酮产物含有二氧化碳和挥发性有机化合物的气态副产物流。这种气态副产物流可以被送入用于加热酮化反应进料流的直接燃烧炉中，挥发性有机化合物在炉内被燃烧销毁。二氧化碳流进一步作为燃料对炉子的稀释剂。
• COMPOUNDS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR
  申请人：Corvus Pharmaceuticals, Inc.

  公开号：EP3616753A1

  公开（公告）日：2020-03-04

  Disclosed herein, inter alia, are compounds of formula (I) and their use in methods for modulating Adenosine Receptors.

  本公开的内容包括式(I)的化合物及其在调节腺苷受体的方法中的应用。
• Crystalline forms of almotriptan and processes for their preparation
  申请人：Sridharan Ramasubramanian

  公开号：US20070112055A1

  公开（公告）日：2007-05-17

  Crystalline forms of almotriptan and almotriptan malate are disclosed. Processes for their preparation and pharmaceutical compositions containing the same are also disclosed. The amorphous form of almotriptan malate, processes for its preparation and a pharmaceutical composition containing the same are also disclosed

  揭示了almotriptan和almotriptan malate的结晶形式。还揭示了它们的制备过程和含有它们的药物组合物。此外，还揭示了almotriptan malate的非晶形式，其制备过程以及含有它的药物组合物。
• Rate controlled release of a pharmaceutical agent in a biodegradable device
  申请人：Kunzler Jay

  公开号：US20070218103A1

  公开（公告）日：2007-09-20

  Matrix controlled diffusion drug delivery systems comprising a therapeutically effective amount of one or more pharmaceutically active agents entrapped in a copolymer which is a reaction product of a monomeric mixture comprising one or more acrylate ester and/or methacrylate ester-containing monomers and one or more acrylamido-containing monomers are disclosed. Also disclosed are processes for their preparations and methods for their use.

  本发明揭示了矩阵控制扩散药物传递系统，其中包括一种或多种药物活性剂的治疗有效量，这些活性剂被困在共聚物中，该共聚物是由单体混合物反应生成的，该单体混合物包括一种或多种丙烯酸酯和/或甲基丙烯酸酯含有单体和一种或多种丙烯酰胺含有单体。还揭示了其制备过程和使用方法。
• Process for the purification of fluconazole
  申请人：Chandrasekhar Batchu

  公开号：US20050282878A1

  公开（公告）日：2005-12-22

  The present invention relates to processes for the purification of crude fluconazole including at least a first leaching, a second leaching, and an acid/base treatment and to highly purified fluconazole produced from the processes.

  本发明涉及粗氟康唑的纯化过程，包括至少一次第一浸提、第二次浸提和酸/碱处理，并涉及由该过程生产的高纯度氟康唑。