pentacosa-10,12-diynoyl chloride | 128937-83-7

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: pentacosa-10,12-diynoyl chloride
• 英文别名: 10,12-pentacosadiynoyl chloride；10,12-pentacosadiynoic acid chloride
• CAS: 128937-83-7
• 化学式: C₂₅H₄₁ClO
• 分子量: 393.053
• InChiKey: WRHLOYBGUWCCEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.1
• 重原子数：
  27
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  pentacosa-10,12-diynoyl chloride 在 ammonium hydroxide 、 lithium aluminium tetrahydride 、 O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate 、 N,N-二异丙基乙胺 作用下， 以 乙醚 、 N,N-二甲基甲酰胺 为溶剂， 反应 37.0h， 生成 (2-{[2-(5-Methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-pentacosa-10,12-diynylcarbamoylmethyl-amino}-ethyl)-carbamic acid tert-butyl ester
  参考文献：
  名称：

  Lipophilic peptide nucleic acids containing a 1,3-diyne function: synthesis, characterization and production of derived polydiacetylene liposomes

  摘要：

  Adenine-, cytosine- and thymine-containing peptide nucleic acid (PNA) monomers have been synthesized in which either diacetylenic or stearoyl moieties are attached to the N-or C-terminus; the diacetylenic group is embedded within a long hydrocarbon chain. A range of analogous lipophilic functionalized PNA oligomers have been prepared using either solid phase synthesis or a post-synthetic solution phase procedure following cleavage of the PNA oligomer from the solid Support. Selected functionalized PNA monomers and oligomers have been incorporated into liposomal polydiacetylenes and characterized by UV-vis absorption spectroscopy. Preliminary investigations show that blue PDA-liposomes containing thymine-based PNAs can be formed and that production of liposomes with other PNA systems are viable. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2005.07.021
• 作为产物：
  描述：

  1-chloro-tetradec-1-yne 在 氢氧化钾 、 氯化亚砜 、 N,N-二甲基甲酰胺 、 甲胺 、 copper(l) chloride 作用下， 以 四氢呋喃 、 甲醇 、 水 、 正戊烷 为溶剂， 反应 5.0h， 生成 pentacosa-10,12-diynoyl chloride
  参考文献：
  名称：

  长链二炔酸的杂环衍生物

  摘要：

  2-氨基吡啶、2-氨基嘧啶、4-氨基-2,2,6,6-四甲基哌啶-1-氧基和4-羟基-2,2,6,6-四甲基哌啶-1-氧基的酰基衍生物获自长链二炔酰氯和相应的杂环化合物。在水表面上展开单层的等温线表明，烃链的延长和这些化合物中的吡啶基被更亲水的嘧啶基取代，使膜更加凝聚。硝酰基自由基的长链酰基衍生物形成具有低塌陷压力的单层。记录了这些自由基在光聚合之前和之后的 Langmuir-Blodgett 膜的 ESR 光谱。

  DOI：

  10.1007/bf00707229

文献信息

• Two-Dimensional Molecular Imprinting: Binding of Sugars to Boronic Acid Functionalized, Polymerized Langmuir–Blodgett Films
  作者：Takashi Miyahara、Kazue Kurihara

  DOI：10.1246/cl.2000.1356

  日期：2000.12

  A molecular imprinted surface was prepared by polymerizing the Langmuir film of a mixture of two polymerizable amphiphiles, one of which has a boronic acid group as a binding site for a template molecule, 4-nitrophenyl α-d-mannopyranoside (3), dissolved in the aqueous subphase. The imprinted surface exhibited an improved affinity (35%) for the template molecule 3 in 2-butanone compared with the non-imprinted surface.

  通过聚合混合了两种可聚合两性分子的朗缪尔膜，制备了一种分子印记表面，其中一种两性分子具有硼酸基团，作为模板分子4-硝基苯基α-D-甘露糖苷（3）的结合位点，该分子溶解于水相基底层中。与非印记表面相比，印记表面在2-丁酮中对模板分子3显示出更高的亲和力（35%）。
• Colorimetric and fluorometric detection of cationic surfactants based on conjugated polydiacetylene supramolecules
  作者：Xiaoqiang Chen、Jung Lee、Min Jung Jou、Jong-Man Kim、Juyoung Yoon

  DOI：10.1039/b904542b

  日期：——

  The polydiacetylenes derived from a hydroxybenzaldehyde substituted diacetylene monomer display a unique colorimetric change (blue to red) and large fluorescent enhancement in the presence of cetyl trimethylammonium salt.

  由羟基苯甲醛取代的双炔单体衍生的聚二乙炔在存在十六烷基三甲基铵盐的情况下，展现出独特的颜色变化（从蓝色变为红色）以及显著的荧光增强现象。
• Polydiacetylene-Based Colorimetric Self-Assembled Vesicular Receptors for Biological Phosphate Ion Recognition
  作者：D. Amilan Jose、Stefan Stadlbauer、Burkhard König

  DOI：10.1002/chem.200900339

  日期：2009.7.27

  Self‐assembled vesicular polydiacetylene (PDA) particles with embedded metal complex receptor sites have been prepared. The particles respond to the presence of ATP and PPi (pyrophosphate) in buffered aqueous solution by visible changes of their color and emission properties. Blue PDA vesicles of uniform size of about 200 nm were obtained upon UV irradiation from mono‐ and dinuclear zinc(II)–cyclen

  制备了具有嵌入的金属络合物受体位点的自组装水泡聚二乙炔（PDA）颗粒。颗粒通过颜色和发射特性的可见变化来响应缓冲水溶液中ATP和PPi（焦磷酸盐）的存在。紫外线照射后，从两核双乙炔单体中嵌入的单核和双核锌（II）-环素和亚氨基二乙二铜[Cu II- IDA]改性的二乙炔获得了均匀大小约为200 nm的蓝色PDA囊泡。将ATP和PPi添加到PDA囊泡溶液中，可以从肉眼观察到的颜色从蓝色变为红色。ATP和PPi的结合会改变发射强度。其它阴离子如ADP，AMP，H 2 PO 4 -，CH 3COO -，F - ，氯- ，溴-和我- ，未能诱导任何光谱变化。锌（II）-周期素纳米粒子可用于方便地检测中性水溶液中毫摩尔浓度的PPi和ATP，而Cu II- IDA修饰的水泡PDA受体能够选择性地区分ATP和PPi。
• 열적 특성이 개선된 도펀트 제조방법 및 이에 따라 제조된 도펀트를 포함하는 전도성 나노 복합체
  申请人：LOTTE CHEMICAL CORPORATION 롯데케미칼 주식회사(119980046011) Corp. No ▼ 110111-0193196BRN ▼118-81-15012

  公开号：KR20190064339A

  公开（公告）日：2019-06-10

  본 발명은 열적 특성이 개선된 도펀트 제조방법 및 이에 따라 제조된 도펀트를 포함하는 전도성 나노 복합체에 관한 것으로, 보다 상세하게는 폴리아닐린에 도핑하여 우수한 전기전도성 및 열적 특성을 나타내는 도펀트 제조방법 및 이에 따라 제조된 도펀트 및 폴리아닐린을 포함하는 전도성 나노 복합체에 관한 것이다. 본 발명에서는 도펀트의 열적안정성을 개선하기 위해 다이아세틸렌 유도체의 한쪽 말단기를 술폰산(sulfonic acid) 또는 벤젠술폰산(Benzenesulfnoic acid)으로 치환하여 술폰산 그룹에 의해 우수한 도핑 특성을 가지며 증가된 아로마틱(Aromatic), 알리파틱(Aliphatic) 그룹으로 인하여 열적안정성이 증가된 도펀트를 우수한 수율로 제조할 수 있는 방법을 제공할 수 있다.

  本发明涉及一种改进热特性的聚合物制备方法以及由此制备的包含聚合物的导电纳米复合材料，更详细地说，涉及一种通过在聚苯胺中掺杂以表现出优异的电导性和热特性的聚合物制备方法，以及由此制备的聚合物和聚苯胺组成的导电纳米复合材料。本发明提供了一种能够以优秀的产率制备出热稳定性改善的聚合物的方法，其中通过将二乙酰乙烯诱导体的一端基取代为磺酸(sulfonic acid)或苯基磺酸(Benzenesulfonic acid)，通过磺酸基团具有优异的掺杂特性，并且由于增加了芳香族(Aromatic)、脂肪族(Aliphatic)基团，可以提高热稳定性。
• Photo-responsive cholesterol-substituted diacetylenic organogels: morphology tuning, photo-switching and photo-polymerization
  作者：Jin Wang、Guang Yang、Hao Jiang、Gang Zou、Qijin Zhang

  DOI：10.1039/c3sm51896e

  日期：——

  A novel cholesterol derivative organogelator (CAZODA) containing both azobenzene and diacetylenic units is synthesized. By using XRD, CD, TEM and SEM characterization, the gelation behavior, microscopic morphology and molecular packing structure in CAZODA assemblies are investigated in detail. It is found that the concentration of the CAZODA at the initial stage plays a crucial role in tuning the microstructure from helical fibers to spherulitic gel networks. Upon UV irradiation at 365 nm, the photo-induced transition of the helical packing structures for CAZODA assemblies has been demonstrated by CD characterization, and an explanation based on the co-assembly of both trans- and cis-form CAZODA has been proposed. In addition, upon irradiation at 254 nm for 3 h, the above organogel can be polymerized with concomitant color change from yellow to red. The polymerized gel exhibits enhanced stability upon thermo or photo-stimuli.

  合成了一种新型胆固醇衍生物有机凝胶剂（CAZODA），其包含了偶氮苯和二乙炔单元。通过使用XRD、CD、TEM和SEM表征，详细研究了CAZODA聚集体中的凝胶行为、微观形态和分子堆积结构。研究发现，CAZODA在初始阶段的浓度在调节微观结构方面起着关键作用，从螺旋纤维转变为球晶状胶体网络。在365 nm的紫外线照射下，利用CD特征表明了CAZODA聚集体螺旋堆积结构的光诱导转变，并提出了基于顺式和反式CAZODA共同组装的解释。此外，在254 nm照射3小时后，上述有机凝胶可以发生聚合，同时颜色从黄色变化为红色。聚合后的胶体在热或光刺激下表现出增强的稳定性。