O-butyl 3-(4-chlorophenyl)-3-oxopropanethioate | 1424273-75-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: O-butyl 3-(4-chlorophenyl)-3-oxopropanethioate
• CAS: 1424273-75-5
• 化学式: C₁₃H₁₅ClO₂S
• 分子量: 270.78
• InChiKey: FNTBIGNPDSZLMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  58.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对氯苯乙酮 在 tin(II) chloride dihdyrate 、 sodium hydride 作用下， 以 正己烷 、 N,N-二甲基甲酰胺 为溶剂， 生成 O-butyl 3-(4-chlorophenyl)-3-oxopropanethioate
  参考文献：
  名称：

  An efficient transesterification of β-oxodithioesters catalyzed by stannous chloride under solvent-free conditions

  摘要：

  Transesterification of beta-oxodithioesters catalyzed by stannous chloride under solvent-free condition has been reported for the first time. The short reaction time and good to excellent yields using inexpensive catalysts are attractive features of this synthetic protocol. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.01.001

文献信息

• An efficient transesterification of β-oxodithioesters catalyzed by stannous chloride under solvent-free conditions
  作者：Nepram Sushuma Devi、Sarangthem Joychandra Singh、Okram Mukherjee Singh

  DOI：10.1016/j.tetlet.2013.01.001

  日期：2013.3

  Transesterification of beta-oxodithioesters catalyzed by stannous chloride under solvent-free condition has been reported for the first time. The short reaction time and good to excellent yields using inexpensive catalysts are attractive features of this synthetic protocol. (C) 2013 Elsevier Ltd. All rights reserved.