(8Z,11Z)-heptadeca-8,11-dien-2-one | 214041-70-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (8Z,11Z)-heptadeca-8,11-dien-2-one
• CAS: 214041-70-0
• 化学式: C₁₇H₃₀O
• 分子量: 250.425
• InChiKey: IKFJCPCTNHFTNH-NQLNTKRDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-methyl-2-((6Z,9Z)-pentadeca-6,9-dienyl)-1,3-dioxolane 在 盐酸 作用下， 以 四氢呋喃 、 水 为溶剂， 以100%的产率得到(8Z,11Z)-heptadeca-8,11-dien-2-one
  参考文献：
  名称：

  紫锥菊和非天然类似物的酮烯烃的合成及其大麻素受体活性。

  摘要：

  尽管紫锥花产品的普及和广泛使用，其功效仍不清楚和有争议。在从紫锥菊中分离出的各种化合物中，仅在淡紫色锥花（E. pallida）中发现的酮烯和酮烯酮是提取物的主要成分。与紫癜链烷酰胺相反，这些化合物尚未合成和研究过免疫刺激作用。我们提出了使用钯催化的交叉偶联反应和对人类大麻素受体的药物合成结果，对酮烯烃的实用和有用的合成方法。所开发的合成路线为酮烯提供了总体良好的收率，并且适用于具有相似的1,4-二烯基序的其他天然产物。在任一受体上均未观察到明显的活性，表明来自E的酮烯。帕利达（Pallida）对通过大麻素系统介导的免疫调节作用不负责任。但是，新合成的非天然类似物在两种大麻素受体上均表现出微摩尔效价。

  DOI：

  10.1002/chem.200801579

文献信息

• Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases
  申请人：——

  公开号：US20030104082A1

  公开（公告）日：2003-06-05

  An improved medical treatment and medicine is provided to quickly and safely resolve HIV and other microbial infections. The inexpensive medicine can be self administered and maintained for the prescribed time. The attractive medicine comprises an antimicrobial concentrate comprising microbe inhibitors, phytochemicals or isolates. Desirably, the effective medicine comprises a surfactant and an aqueous carrier or solvent and a nutrient. In the preferred form, the medicine comprises: Echinacea and Commiphora myrrha phytochemicals, benzalkonium chloride, a sterile water solution, and folic acid.

  提供了一种改进的医疗方法和药物，可快速、安全地解决艾滋病毒和其他微生物感染问题。这种药物价格低廉，可自行服用并在规定时间内维持。这种有吸引力的药物包括一种抗微生物浓缩物，其中含有微生物抑制剂、植物化学物质或分离物。理想情况下，有效药物包括表面活性剂和水性载体或溶剂以及营养素。在优选形式中，药物包括紫锥菊和 紫锥菊 植物化学物质、苯扎氯铵、无菌水溶液和叶酸。
• Composition to Treat Herpes, Pseudomonas, Staph, Hepatitis and Other Infectious Diseases
  申请人：Squires Meryl J.

  公开号：US20090191288A1

  公开（公告）日：2009-07-30

  An improved method (process) and medicinal composition is provided to treat herpes, pseudomonas, hepatitis, staph (staphylococci) and other infectious diseases The inexpensive medicinal composition can be self-administered and maintained for a prescribed time. The attractive medicinal composition can comprise a quaternary ammonium salt surfactant, a skin protectant and an alcohol. The quaternary ammonium salt surfactant can comprise benzalkonium halide, preferably benzalkonium chloride. The skin protectant can comprise Allantoin. The alcohol can serve as a pain reliever and can comprise benzyl alcohol. The medicinal composition can also include other compounds, additives, herbal extracts and/or carriers.
• Medicinal Composition
  申请人：Squires Meryl J.

  公开号：US20100303935A1

  公开（公告）日：2010-12-02

  A medicinal composition comprising herbal extracts of herbaceous botanicals that can help provide relief of various ailments. The medicinal composition can comprise a topical analgesic with therapeutic benefits for use in humans, equine, bovine, canine, feline, porcine, or other animals or birds for treatment, healing or relieving symptoms resulting from injured ligaments, tendons, muscles, bones, hematomas, nerves, or sports injuries or for epidermal or dermal treatment or relief of conditions or symptoms caused by arthritis, neuralgia, or pain. The herbaceous botanicals of the preferred herbal extracts of herbaceous botanicals in this application can include: Bellis Perennis (Daisy), Ruta Graveolens (Rue), Comfrey, Elder, Hops, Echinacea, Hypericum Perforatum (St. John's Wart), Aloe Vera , Mistletoe, Rhus toxicodendron (Poison Ivy), Eucalyptus, Commiphora myrrha , Goldenseal, and Cayenne. Furthermore, the medicinal composition can include Benzalkonium halide, such as Benzalkonium halide chloride, as well as at least one compound comprising Menthol or a diluent comprising distilled water and/or Isopropyl Alcohol.
• Treatment of Herpes, Pseudomonas, Staph, and Hepatitis
  申请人：Squires Meryl J.

  公开号：US20160151436A1

  公开（公告）日：2016-06-02

  An improved method (process) is provided to treat herpes, pseudomonas, staphylococcus (staph), and hepatitis and help treat or alleviate cold sores, rashes, skin conditions, or symptoms resulting from herpes, pseudomonas, staph, and hepatitis. The method uses a special medicinal composition which can be self-administered and maintained for a prescribed time. The attractive medicinal composition can comprise a quaternary ammonium salt surfactant, a skin protectant and an alcohol. The quaternary ammonium salt surfactant can comprise benzalkonium halide, preferably benzalkonium chloride. The skin protectant can comprise Allantoin. The alcohol can serve as a pain reliever and can comprise benzyl alcohol. The medicinal composition can also include other compounds, additives, herbal extracts and/or carriers. Desirably, the medicinal composition is maintained on the infected regions until external symptoms and physical manifestations of the symptoms resulting from herpes, pseudomonas, hepatitis, or staph substantially disappear from the infected regions.
• US6350784B1
  申请人：——

  公开号：US6350784B1

  公开（公告）日：2002-02-26