Caffeic acid-4-O-sulfate | 151481-51-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: Caffeic acid-4-O-sulfate
• 英文别名: caffeic acid 4'-O-sulfate；caffeic acid-4'-sulfate；Caffeic acid 4-sulfate；(E)-3-(3-hydroxy-4-sulfooxyphenyl)prop-2-enoic acid
• CAS: 151481-51-5
• 化学式: C₉H₈O₇S
• 分子量: 260.224
• InChiKey: SNVAIAITQIIEMQ-DUXPYHPUSA-N

物化性质

• 密度：
  1.740±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  130
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  TRANS-咖啡酸 在 氯磺酸 作用下， 以 吡啶 为溶剂， 生成 Caffeic acid-4-O-sulfate
  参考文献：
  名称：

  The antifouling activity of natural and synthetic phenol acid sulphate esters

  摘要：

  p-(sulphooxy) Cinnamic acid was isolated as a natural product for the first time from the seagrass Zostera marina (eelgrass) and was found to prevent attachment of marine bacteria and barnacles to artificial surfaces at non-toxic concentrations. Analogous synthetic sulphate esters had similar antifouling properties, while the non-sulphated phenolic acid precursors were ineffective. The antifouling properties of phenolic acid sulphates are consistent with an emerging pattern of biological activity exhibited by other sulphate esters isolated from a variety of marine organisms, and their low toxicity offers promise for the development of environmentally benign antifouling agents to protect structures in aquatic environments.

  DOI：

  10.1016/0031-9422(93)80017-m

文献信息

• GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3071235A1

  公开（公告）日：2016-09-28
• GLYCAN COMPOSITIONS AND USES THEREOF
  申请人：Kaleido Biosciences, Inc.

  公开号：EP3334437A1

  公开（公告）日：2018-06-20
• [EN] GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF<br/>[FR] COMPOSITIONS THÉRAPEUTIQUES DE GYLCANE ET PROCÉDÉS ASSOCIÉS
  申请人：KALEIDO BIOSCIENCES INC

  公开号：WO2016122889A1

  公开（公告）日：2016-08-04

  Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
• [EN] GLYCAN COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS DE GLYCANE ET LEURS UTILISATIONS
  申请人：KALEIDO BIOSCIENCES INC

  公开号：WO2017035412A1

  公开（公告）日：2017-03-02

  Compositions comprising glycan preparations suitable for local administration to non-gut sites containing mucosal tissue, e.g., oral cavity, nasal cavity and vagina are provided. Further provided are methods of using said glycan preparations.
• The antifouling activity of natural and synthetic phenol acid sulphate esters
  作者：James S. Todd、Richard C. Zimmerman、Phillip Crews、Randall S. Alberte

  DOI：10.1016/0031-9422(93)80017-m

  日期：1993.9

  p-(sulphooxy) Cinnamic acid was isolated as a natural product for the first time from the seagrass Zostera marina (eelgrass) and was found to prevent attachment of marine bacteria and barnacles to artificial surfaces at non-toxic concentrations. Analogous synthetic sulphate esters had similar antifouling properties, while the non-sulphated phenolic acid precursors were ineffective. The antifouling properties of phenolic acid sulphates are consistent with an emerging pattern of biological activity exhibited by other sulphate esters isolated from a variety of marine organisms, and their low toxicity offers promise for the development of environmentally benign antifouling agents to protect structures in aquatic environments.