5-ethyl-3-methylcyclopent-2-en-1-one | 90198-70-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-ethyl-3-methylcyclopent-2-en-1-one
• 英文别名: 5-ethyl-3-methylcyclopent-2-enone；3-Methyl-5-ethyl-Δ²-cyclopentenon-(1)
• CAS: 90198-70-2
• 化学式: C₈H₁₂O
• 分子量: 124.183
• InChiKey: WDWWQVKTPZPZPU-UHFFFAOYSA-N

物化性质

• 沸点：
  57-59 °C(Press: 5 Torr)
• 密度：
  0.9502 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-ethyl-3-methylcyclopent-2-en-1-one 在 铂 氢气 作用下， 生成 4-Methyl-2-ethyl-cyclopentanon-(1)
  参考文献：
  名称：

  Chemistry of cyclopentenones

  摘要：

  DOI：

  10.1007/bf00911368
• 作为产物：
  描述：

  3,5-Dimethyl-5-vinyl-Δ²-cyclopentenon-(1) 在 palladium on activated charcoal 作用下， 生成 5-ethyl-3-methylcyclopent-2-en-1-one
  参考文献：
  名称：

  Chemistry of cyclopentenones

  摘要：

  DOI：

  10.1007/bf00911368

文献信息

• Manganese(III) acetate based oxidation of substituted α′-position on cyclic α,β-unsaturated ketones
  作者：Cihangir Tanyeli、Çigdem Iyigün

  DOI：10.1016/s0040-4020(03)01094-9

  日期：2003.9

  Selective oxidation of the tertiary α′-position on various 2-cyclopentenone, 2-cyclohexenone and aromatic ketone derivatives with manganese(III) acetate is described.

  描述了用乙酸锰（III）选择性氧化各种2-环戊烯酮，2-环己烯酮和芳族酮衍生物上的叔α'-位置。
• New Cyclotrimerization of Aldehydes to Cyclopentenone or Tetrahydrofuran Induced by Dibromotriphenylphosphorane
  作者：Marie-Pierre Heck、Christophe Matt、Alain Wagner、Loïc Toupet、Charles Mioskowski

  DOI：10.1002/ejoc.200901105

  日期：2010.2

  alpha-Mono- or alpha-dialkylated aldehydes undergo cyclotrimerization in the presence of dibromotriphenylphosphorane (PPh(3)Br(2)) to afford cyclopentenones or tetrasubstituted tetrahydrofurans in good yields. These transformations proceed by a tandem aldol dimerization/Nazarov reaction or a tandem aldol dimerization/Prins cyclization.

  α-单-或 α-二烷基化醛在二溴三苯基正膦 (PPh(3)Br(2)) 存在下发生环三聚反应，以良好的收率得到环戊烯酮或四取代的四氢呋喃。这些转化通过串联羟醛二聚/Nazarov 反应或串联羟醛二聚/Prins 环化进行。
• The first enzymatic resolution of quaternary α′-acetoxy α,β-unsaturated cyclohexenones and cyclopentenones
  作者：Cihangir Tanyeli、Fazilet Devrim Özdemirhan、Çiğdem İyigün

  DOI：10.1016/j.tetasy.2005.11.016

  日期：2005.12

  The enantio selective resolution of various quaternary alpha'-acetoxy alpha,beta-unsaturated cyclohexenones and cyclopentenones was performed with the commercially available enzyme CCL in pH = 8.0 phosphate buffer. Various parameters that would affect the enantioselectivities were tested and the best enzymatic resolution conditions were found to afford the enantiomerically enriched quaternary acetoxylated substrates with high ee varying between 36% and 99%. (c) 2005 Elsevier Ltd. All rights reserved.
• Campi, Eva M.; Jackson, W. Roy, Australian Journal of Chemistry, 1989, vol. 42, # 4, p. 471 - 478
  作者：Campi, Eva M.、Jackson, W. Roy

  DOI：——

  日期：——
• Chemistry of cyclopentenones
  作者：A. N. Elizarova、T. E. Pozdnyakova、A. A. Akhrem

  DOI：10.1007/bf00911368

  日期：1962.12