5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole | 66401-83-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole
• 英文别名: 2-(2-hydroxy-5-amino-phenyl)-5-aminobenzoxazole；Phenol, 4-amino-2-(5-amino-2-benzoxazolyl)-；4-amino-2-(5-amino-1,3-benzoxazol-2-yl)phenol
• CAS: 66401-83-0
• 化学式: C₁₃H₁₁N₃O₂
• 分子量: 241.249
• InChiKey: UZKHGLOOTRAUDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  98.3
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole 在 sodium nitrate 、 copper bromide 、 氢溴酸 作用下， 反应 5.0h， 以57%的产率得到5-bromo-2-(5'-bromo-2'-hydroxyphenyl)benzoxazole
  参考文献：
  名称：

  Synthesis of Fluorescent Probe Sensitive to Amine

  摘要：

  5-Bromo-2-(5'-bromo-2'-hydroxyphenyl)benzoxazole 4 is prepared from the Sandmeyer reaction of 5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole 3 with copper bromide. Two kinds of the (hydroxyphenyl)benzoxazole compounds are investigated for application in fluorescent probe sensing amino compounds and compound 4 is proved to be more suitable for sensing haxamethylenediamine and hydrazine with different fluorescent colors.

  DOI：

  10.1080/15421400490506252
• 作为产物：
  描述：

  2-(2-hydroxy-5-nitrophenyl)-5-nitrobenzoxazole 在 palladium 10% on activated carbon 、 一水合肼 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以92.4%的产率得到5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole
  参考文献：
  名称：

  一种含羟基苯并噁唑二胺的制备方法

  摘要：

  本发明提供了一种含羟基苯并噁唑二胺的制备方法，包括以下步骤：a)将苯甲醛化合物、苯胺化合物和催化剂在溶剂中混合，进行缩合反应，得到苯并噁唑化合物；所述催化剂为PCl3；b)将步骤a)得到的苯并噁唑化合物进行还原反应，得到含羟基苯并噁唑二胺；所述含羟基苯并噁唑二胺具有式(IV)、式(VII)或式(X)所示结构。与现有技术相比，本发明通过多步法，首先通过缩合反应制备含羟基的二硝基苯并噁唑，再通过还原反应制备含羟基苯并噁唑二胺，采用本发明提供的制备方法得到的含羟基苯并噁唑二胺的收率高。实验结果表明，本发明提供的制备方法得到的含羟基苯并噁唑二胺的收率大于79％。

  公开号：

  CN105237547B

文献信息

• Gelation-induced fluorescence enhancement of benzoxazole-based organogel and its naked-eye fluoride detection
  作者：Tae Hyeon Kim、Moon Soo Choi、Byeong-Hyeok Sohn、Soo-Young Park、Won Seok Lyoo、Taek Seung Lee

  DOI：10.1039/b800813b

  日期：——

  The benzoxazole derivative gelator 1 forms a stable DMF/toluene cosolvent gel with dramatically enhanced fluorescence emission compared to its mother solution. The translucent colorless gel was changed to a solution with strong greenish fluorescence in the presence of fluoride anion with disruption of the gel structure.

  苯并噁唑衍生物凝胶剂1在DMF/甲苯共溶剂中形成了一种稳定性强的凝胶，其荧光发射强度相比母液显著增强。这种透明无色的凝胶，在氟离子存在下，由于凝胶结构的破坏，转变为一种具有强烈绿色荧光的溶液。
• POLYIMIDE FIBER AND PREPARATION METHOD THEREFOR
  申请人：Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences

  公开号：EP3378976A1

  公开（公告）日：2018-09-26

  This application provides a polyimide fiber and a preparation method thereof. This method comprises first subjecting a dianhydride compound and a diamine compound to a polymerization reaction in a solvent to obtain a polyamic acid solution, wherein said diamine compound comprises a diamine having a structure of Formula 12 or Formula 13, wherein A is S or O; said dianhydride compound comprises one or more of dianhydrides having structures of Formula 14 and Formula 15; and t is 0 or 1; then subjecting said polyamic acid solution to spinning to obtain a polyamic acid fiber; and sequentially subjecting said polyamic acid fiber to imidization and thermal drawing to obtain a polyimide fiber. The polyimide fiber having the above structure has a higher rigidity and can introduce a hydrogen bond to provide an interaction between molecular chains so as to influence the arrangement of the molecular chain in the polymer and the crystallinity, which imparts more excellent mechanical properties to the polyimide fiber. The polyimide fiber obtained has a higher glass transition temperature (Tg) and a better heat resistance.

  本申请提供了一种聚酰亚胺纤维及其制备方法。该方法包括首先将二酐化合物和二胺化合物在溶剂中进行聚合反应以获得聚酰胺酸溶液，其中所述二胺化合物包括具有式 12 或式 13 结构的二胺，其中 A 为 S 或 O；所述二酐化合物包括具有式 14 和式 15 结构的一种或多种二酐；以及 t 为 0 或 1；然后将所述聚酰胺酸溶液进行纺丝，以获得聚酰胺酸纤维；并依次将所述聚酰胺酸纤维进行酰亚胺化和热拉伸，以获得聚酰亚胺纤维。具有上述结构的聚酰亚胺纤维具有更高的刚性，并能引入氢键，提供分子链之间的相互作用，从而影响聚合物中分子链的排列和结晶度，使聚酰亚胺纤维具有更优异的机械性能。得到的聚酰亚胺纤维具有更高的玻璃化温度（Tg）和更好的耐热性。
• SKOPENKO, V. N.;OLSHEVSKAYA, I. A.;POCHINOK, V. YA.;OLXOVIK, L. A., YKP. XIM. ZH., 1985, 51, N 3, 316-320
  作者：SKOPENKO, V. N.、OLSHEVSKAYA, I. A.、POCHINOK, V. YA.、OLXOVIK, L. A.

  DOI：——

  日期：——
• POLYMIDE FIBER AND PREPARATION METHOD THEREOF
  申请人：CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES

  公开号：US20180282907A1

  公开（公告）日：2018-10-04

  This application provides a polyimide fiber and a preparation method thereof. This method comprises first subjecting a dianhydride compound and a diamine compound to a polymerization reaction in a solvent to obtain a polyamic acid solution, wherein said diamine compound comprises a diamine having a structure of Formula 12 or Formula 13, wherein A is S or O; said dianhydride compound comprises one or more of dianhydrides having structures of Formula 14 and Formula 15; and t is 0 or 1; then subjecting said polyamic acid solution to spinning to obtain a polyamic acid fiber; and sequentially subjecting said polyamic acid fiber to imidization and thermal drawing to obtain a polyimide fiber. The polyimide fiber having the above structure has a higher rigidity and can introduce a hydrogen bond to provide an interaction between molecular chains so as to influence the arrangement of the molecular chain in the polymer and the crystallinity, which imparts more excellent mechanical properties to the polyimide fiber. The polyimide fiber obtained has a higher glass transition temperature (Tg) and a better heat resistance.
• Synthesis of Fluorescent Probe Sensitive to Amine
  作者：Jin Lee、Jongho Na、Won Park、Taek Lee、Yong Kwon

  DOI：10.1080/15421400490506252

  日期：2004.1

  5-Bromo-2-(5'-bromo-2'-hydroxyphenyl)benzoxazole 4 is prepared from the Sandmeyer reaction of 5-amino-2-(5'-amino-2'-hydroxyphenyl)benzoxazole 3 with copper bromide. Two kinds of the (hydroxyphenyl)benzoxazole compounds are investigated for application in fluorescent probe sensing amino compounds and compound 4 is proved to be more suitable for sensing haxamethylenediamine and hydrazine with different fluorescent colors.