cinnamic acid triethanolammonium salt | 65527-55-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: cinnamic acid triethanolammonium salt
• 英文别名: [TEAH](Cin)；Einecs 265-810-0；2-[bis(2-hydroxyethyl)amino]ethanol;(E)-3-phenylprop-2-enoic acid
• CAS: 65527-55-1
• 化学式: C₆H₁₅NO₃*C₉H₈O₂
• 分子量: 297.351
• InChiKey: VUMGITRPAMHUFV-UHDJGPCESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.05
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  101
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  三乙醇胺 、 肉桂酸 以 甲醇 为溶剂， 反应 1.0h， 以95%的产率得到cinnamic acid triethanolammonium salt
  参考文献：
  名称：

  生物活性羧酸的三乙醇铵盐

  摘要：

  合成的生物活性羧酸（烟酸，肉桂酸，苯甲酸，水杨酸，草酸，丙二酸，琥珀酸，苹果酸，柠檬酸）的三乙醇铵盐（protatranes）的收率超过90％。通过红外光谱和X射线衍射分析研究了合成化合物的结构。

  DOI：

  10.1134/s1070363215120075

文献信息

• Biological Activity of Protic Ionic Liquids Based on Tris(2-hydroxyethyl)ammonium Salts and the Crystal Structure of Tris(2-hydroxyethyl)ammonium Malate
  作者：Yu. A. Kondratenko、V. V. Gurzhii、G. G. Panova、L. M. Anikina、O. R. Udalova、V. I. Krutikov、V. L. Ugolkov、T. A. Kochina

  DOI：10.1134/s0036023620090089

  日期：2020.9

  The antimicrobial and growth-stimulating activities of nine protic ionic liquids (PILs)-tris(2-hydroxyethyl)ammonium salts (protatranes) of cinnamic, benzoic, salicylic, oxalic, malonic, succinic, malic and citric acids-were investigated for the first time. It was found that tris(2-hydroxyethyl)ammonium salts of cinnamic, benzoic and malonic acids have a positive impact on seeds germination and growth characteristics of garden cress (Lepidium sativumL.) sprouts. All the investigated PILs exhibited selective activity againstStaphylococcus aureusbacteria.PILs based on tris(2-hydroxyethyl)ammonium malate with the melting point of 41 degrees C were isolated as crystals to perform a comparative study of the crystal structure by single-crystal X-ray diffraction. In contrast to cations in tris(2-hydroxyethyl)ammonium succinate, cations in malate have a tricyclicendoconformation that is most typical of tris(2-hydroxyethyl)ammonium salts.
• US4033886A
  申请人：——

  公开号：US4033886A

  公开（公告）日：1977-07-05