trans-1,4-dichlorocyclohexane | 16890-91-8

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 环烃
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: trans-1,4-dichlorocyclohexane
• 英文别名: trans-1,4-dichloro-cyclohexane；trans-1,4-Dichlor-cyclohexan
• CAS: 16890-91-8
• 化学式: C₆H₁₀Cl₂
• 分子量: 153.051
• InChiKey: WQTINZDWAXJLGH-IZLXSQMJSA-N

物化性质

• 熔点：
  103 °C
• 沸点：
  60 °C / 3mmHg
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.78
• 重原子数：
  8.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

安全信息

• 海关编码：
  2903890090
• 储存条件：
  室温

SDS

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Section I.Chemical Product and Company Identification
Chemical Name trans-1,4-Dichlorocyclohexane
Portland OR
Synonym Not available.
Chemical Formula C6H10Cl2
CAS Number 16890-91-8

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Section II. Composition and Information on Ingredients
Chemical Name CAS Number Percent (%) TLV/PEL Toxicology Data
trans-1,4-Dichlorocyclohexane 16890-91-8 Min. 99.0 Not available. Not available.
(GC)

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Section III. Hazards Identification
Acute Health Effects No specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is
not known to aggravate existing medical conditions.

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Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum
of 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and
supportively.
Skin Contact After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with
running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the
irritated skin with an emollient. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated
clothing before reusing.
Inhalation If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If
breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively.
Ingestion INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration.
Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material
was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible,
show the chemical label. Treat symptomatically and supportively.

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Section V. Fire and Explosion Data
Not available.
Flammability Combustible. Auto-Ignition
Flammable Limits
Flash Points Not available.
Not available.
Combustion Products These products are toxic carbon oxides (CO, CO 2), halogenated compounds.
WARNING: Highly toxic HCl gas is produced during combustion.
Fire Hazards
No specific information is available regarding the flammability of this compound in the presence of various materials.
Explosion Hazards Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
No additional information is available regarding the risks of explosion.
Fire Fighting Media
SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam.
and Instructions LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Continued on Next Page
trans-1,4-Dichlorocyclohexane

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Section VI. Accidental Release Measures
Spill Cleanup In case of a spill and/or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a
Instructions shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
disposal.

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Section VII. Handling and Storage
Handling and Storage Keep away from heat and sources of ignition. Mechanical exhaust required. When not in use, tightly seal the container
and store in a dry, cool place. Avoid excessive heat and light. DO NOT breathe dust. In case of insufficient ventilation,
Information
wear suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Treat
symptomatically and supportively. Avoid contact with skin and eyes.
Always store away from incompatible compounds such as oxidizing agents.

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Section VIII. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
this product.
Exposure Limits Not available.

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Section IX. Physical and Chemical Properties
Physical state @ 20°C Crystalline powder. Solubility
Not available.
Not available.
Specific Gravity
Molecular Weight 153.05 Partition Coefficient
Not available.
Boiling Point Not available. Vapor Pressure Not available.
Melting Point 103°C (217.4°F) Vapor Density Not available.
Not available. Not available.
Refractive Index Volatility
Critical Temperature Not available. Odor Not available.
Viscosity Not available. Taste Not available.

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Section X. Stability and Reactivity Data
Stability

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This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability
Avoid excessive heat and light.
Incompatibilities
Reactive with oxidizing agents.

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Section XI. Toxicological Information
RTECS Number Not available.
Routes of Exposure Eye contact. Inhalation. Ingestion.
Not available.
Toxicity Data
CARCINOGENIC EFFECTS : Not available.
Chronic Toxic Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure to this compound is not
known to aggravate existing medical conditions.
Acute Toxic Effects No specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
Continued on Next Page
trans-1,4-Dichlorocyclohexane

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Section XII. Ecological Information
Ecotoxicity Not available.
Environmental Fate Not available.

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Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with
Waste Disposal
a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state, and local regulations when disposing of this substance.

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Section XIV. Transport Information
DOT Classification Not a DOT controlled material (United States).
PIN Number Not applicable.
Proper Shipping Name
Not applicable.
Packing Group (PG) Not applicable.
DOT Pictograms

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Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS Classification Not controlled under WHMIS (Canada).
(Canada)
EINECS Number (EEC) Not available.
EEC Risk Statements Not controlled under DSCL (Europe).

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  trans-1,4-dichlorocyclohexane 、 1,4-cis-dichlorocyclohexane 、 苯酚 在 三氯化铝 、 Petroleum ether 作用下， 生成 1,2,3,4-tetrahydro-1,4-ethano-naphthalen-6-ol
  参考文献：
  名称：

  MEMS for Light-Wave Networks

  摘要：

  正如本问题所展示的，新兴的微机电系统（MEMS）领域开始影响几乎所有科学技术领域。MEMS有潜力彻底改变光波系统。诸如光开关、可变衰减器、主动均衡器、加/波分复用器（ADM）、光交叉连接器（OXC）、增益倾斜均衡器、数据发射器等微器件开始在先进的光波系统中找到广泛应用。

  DOI：

  10.1557/mrs2001.73
• 作为产物：
  描述：

  trans-Cyclohexane-1,4-diol 在 盐酸 作用下， 生成 trans-1,4-dichlorocyclohexane
  参考文献：
  名称：

  Rothstein, Annales de Chimie (Cachan, France), 1930, vol. <10> 14, p. 461,515

  摘要：

  DOI：

文献信息

• METHOD OF PRODUCING CATALYST COMPONENT FOR OLEFIN POLYMERIZATION
  申请人：Tonen Corporation

  公开号：EP0440813A1

  公开（公告）日：1991-08-14

  A method of effectively producing an olefin polymerization catalyst component which exhibits a high activity of polymerizing an olefin to give a polymer having a reduced content of low molecular components, said method comprising bringing into contact with one another (a) metallic magnesium, (b) a halogenated hydrocarbon represented by a general formula RX, wherein R represents C₁ to C₂₀ alkyl, aryl or cycloalkyl, and X represents halogen, and (c) a compound of a general formula X¹nM(OR¹)m-n, wherein X¹ represents hydrogen, halogen or C₁ to C₂₀ hydrocarbyl, M represents boron, carbon, aluminum, silicon or phosphorus, R¹ represents C₁ to C₂₀ hydrocarbyl, m is a valence of M, and m > n ≧ 0, to give a magnesium-containing solid; bringing the solid into contact with a halogenated alcohol; and bringing the product of contact further into contact with a titanium compound and a solid halogenated hydrocarbon.

  一种有效生产烯烃聚合催化剂组分的方法，该组分具有聚合烯烃的高活性，从而得到低分子组分含量降低的聚合物，所述方法包括使以下物质相互接触：(a)金属镁；(b)通式 RX.代表的卤代烃，其中 R 代表 C₁至 C₂₀烷基、芳基或环烷基；以及 X 代表卤素、其中 R 代表 C₁ 至 C₂₀ 烷基、芳基或环烷基，X 代表卤素，以及 (c) 通式 X¹nM(OR¹)m-n 的化合物，其中 X¹ 代表氢、卤素或 C₁ 至 C₂₀ 烃基、M 代表硼、碳、铝、硅或磷，R¹ 代表 C₁ 至 C₂₀烃基，m 是 M 的化合价，且 m > n ≧ 0，从而得到含镁固体；使固体与卤代醇接触；以及使接触产物进一步与钛化合物和固体卤代烃接触。
• Quinazoline and indole compounds to treat medical disorders
  申请人：Achillion Pharmaceuticals, Inc.

  公开号：US10961252B2

  公开（公告）日：2021-03-30

  Compounds, methods of use, and processes for making inhibitors of Complement Factor B are provided.

  本研究提供了用于制造补体因子 B 抑制剂的化合物、使用方法和工艺。
• Kinetic analysis of alkane polychlorination with molecular chlorine. Chlorine atom/monochloride geminate pairs and the effect of reactive cage walls on the competition between monochloride rotation and chlorine atom escape
  作者：K. D. Raner、J. Lusztyk、K. U. Ingold

  DOI：10.1021/ja00219a028

  日期：1988.5
• The Reaction of cis-1,4-Epoxycyclohexane with Hydrochloric Acid and with Hydrobromic Acid
  作者：Edward L. Bennett、Carl Niemann

  DOI：10.1021/ja01140a024

  日期：1952.10
• Palfray; Rothstein, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1930, vol. 190, p. 190
  作者：Palfray、Rothstein

  DOI：——

  日期：——