2,4,5-trimethyl-hexan-3-one | 23936-98-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4,5-trimethyl-hexan-3-one
• 英文别名: 2,4,5-Trimethyl-hexan-3-on；2,4,5-Trimethylhexan-3-one
• CAS: 23936-98-3
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: WKSICMXNJHMHKY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2,4,5-三甲基-己-4-烯-3-酮 、 2,4,5-trimethyl-hex-5-en-3-one 在 铂 作用下， 生成 2,4,5-trimethyl-hexan-3-one
  参考文献：
  名称：

  Colonge; Mostafavi, Bulletin de la Societe Chimique de France, 1939, vol. <5>6, p. 344

  摘要：

  DOI：

文献信息

• CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION
  申请人：Fresenius Kabi Deutschland GmbH

  公开号：US20150297738A1

  公开（公告）日：2015-10-22

  The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M) n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS′ is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.

  本发明涉及一种羟烷基淀粉共轭物及其制备方法，所述羟烷基淀粉共轭物包括羟烷基淀粉衍生物和细胞毒性药剂，所述细胞毒性药剂包括至少一个次级羟基，其中羟烷基淀粉通过所述次级羟基与细胞毒性药剂连接。根据本发明的共轭物具有以下公式HAS'(-L-M)n的结构，其中M是细胞毒性药剂的残基，L是连接基团，HAS'是羟烷基淀粉衍生物的残基，n大于或等于1，且羟烷基淀粉衍生物的平均分子量（MW）高于肾脏阈值。
• Catalytic synthesis of oxygenate from alcohol
  申请人：Yuan Ze University

  公开号：US07314960B1

  公开（公告）日：2008-01-01

  The present invention discloses a method for catalytic synthesis of oxygenate from alcohol. At first, a feeding material comprising at least one alcohol is provided. Next, a copper-containing catalyst is provided and the catalyst further comprises at least one metal element selected from the group consisting of the following: zinc, magnesium, and aluminum elements. Following that, a catalytic reaction of the feeding material over the copper-containing catalyst is carried out to synthesize at least one oxygenate.

  本发明公开了一种从醇类催化合成氧化物的方法。首先，提供一种包含至少一种醇类的进料材料。接下来，提供含铜催化剂，该催化剂进一步包括以下组中选择的至少一种金属元素：锌、镁和铝元素。随后，在含铜催化剂上进行进料材料的催化反应，以合成至少一种氧化物。
• Reduction-methylation of derivatives of 3-buten-2-one
  作者：Lawrence E. Hightower、Lowrie R. Glasgow、Kearfott Stone、David A. Albertson、Homer A. Smith

  DOI：10.1021/jo00831a035

  日期：1970.6
• COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY
  申请人：Siddiqui M. Arshad

  公开号：US20110171172A1

  公开（公告）日：2011-07-14

  The present invention relates to compounds of Formula (I), below, (wherein R 1 , R 2 , R 3 , p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity.
• PROTECTIVE ACTION OF SEROFENDIC ACID ON CARDIAC MUSCLE
  申请人：Akao Masaharu

  公开号：US20120115951A1

  公开（公告）日：2012-05-10

  A cardiac myocyte protective agent, comprising a compound represented by the formula (Ia) below, a pharmaceutically acceptable salt thereof, or a solvate thereof: