D-glycero-D-galacto-heptonic acid | 689208-16-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: D-glycero-D-galacto-heptonic acid
• 英文别名: D-glycero-D-galacto-Heptonsaeure；D-glycero-D-galakto-Heptonsaeure；D-Manno-D-gala-heptonsaeure；D-Manno-D-heptonsaeure；D-Manno-α-heptonsaeure；(2R,3S,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoic acid
• CAS: 689208-16-0
• 化学式: C₇H₁₄O₈
• 分子量: 226.183
• InChiKey: KWMLJOLKUYYJFJ-RWOPYEJCSA-N

物化性质

• 沸点：
  727.8±60.0 °C(Predicted)
• 密度：
  1.800±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  159
• 氢给体数：
  7
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  D-glycero-D-galacto-heptonic acid 在 吡啶 、 水 作用下， 生成 D-glycero-D-talo-heptonic acid
  参考文献：
  名称：

  Ettel, Collection of Czechoslovak Chemical Communications, 1932, vol. 4, p. 512

  摘要：

  DOI：
• 作为产物：
  描述：

  D-glycero-D-talo-heptonic acid 在 吡啶 、 水 作用下， 生成 D-glycero-D-galacto-heptonic acid
  参考文献：
  名称：

  Peirce, Journal of Biological Chemistry, 1915, vol. 23, p. 337

  摘要：

  DOI：

文献信息

• Fischer,E.; Hirschberger, Chemische Berichte, 1889, vol. 22, p. 370
  作者：Fischer,E.、Hirschberger

  DOI：——

  日期：——
• Kiliani, Chemische Berichte, 1930, vol. 63, p. 369,370
  作者：Kiliani

  DOI：——

  日期：——
• Hudson; Hartley; Purves, Journal of the American Chemical Society, 1934, vol. 56, p. 1249
  作者：Hudson、Hartley、Purves

  DOI：——

  日期：——
• Isbell, Journal of Research of the National Bureau of Standards (United States), 1937, vol. 19, p. 646
  作者：Isbell

  DOI：——

  日期：——
• Increasingly inequitable distribution of general practitioners in Australia, 1986–96
  作者：Greg Johnston、David Wilkinson

  DOI：10.1111/j.1467-842x.2001.tb00553.x

  日期：2001.2

  Objective: To document trends in the distribution of general practitioners (GPs) in Australia between 1986 and 1996, adjusted for community need.Methods: Data on the location of GPs, population size and crude mortality in statistical divisions (SD) were obtained from the Australian Bureau of Statistics Census of Population and Housing in 1986 and 1996. From these data, we calculated measures of distribution equality (number of people sharing each GP in each SD) and distribution equity (number of people sharing each GP divided by the crude mortality rate; the Robin Hood Index), and analysed temporal changes in the distribution of GPs.Results: Nationally the number of people sharing each GP fell 11% from 1,038 in 1986 to 921 in 1996. However, in 41 of 57 SDs (72%, p=0.01) the number of people sharing a GP actually increased over this time, and the average Robin Hood Index across SDs fell from 0.943 to 0.783 (p=0.004), indicating increasingly inequitable distribution. Comparing the Robin Hood index values of all SDs ranked in pairs, the value fell in 53 of 57 (93%, p<0.001) paired SDs over the decade. These patterns demonstrate increasing inequity over the decade. The number of people sharing each GP was consistently and substantially lower in the capital city SDs and the Robin Hood Index values were consistently and substantially higher (overserved) compared with country SDs.Conclusions: Despite there being more GPs per capita in Australia, their distribution became increasingly unequal and inequitable between 1986 and 1996, such that rural and remote areas became increasingly poorly served.